cell necrosis Flashcards

1
Q

two types of cell death

A

apoptosis and necrosis

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2
Q

gross histologuc correlate of cell death

A

necrosis

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3
Q

what organelle causes cell death due to its enzymes

A

lysosomes

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4
Q

apoptosis always has inflammation

A

false

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5
Q

morphology od necrosis under microscope

A

increased eosinophilia, myelin figures, glassy homogenous figures, nucleu¥ar changes, calcification

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6
Q

develops presence of denaturation

A

coagulative necrosis

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7
Q

does not denote pattern of necrosis

A

fat necrosis

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8
Q

seen in the brain

A

liquefactive necrosis

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9
Q

cheesy white gross appearance

A

caseous necrosis

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10
Q

fat necrosis is due to

A

fat lipases

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11
Q

due to focal bacterial or fungal

A

liquefactive necrosis

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12
Q

induced by tightly regulated intracellular program

A

apoptosis

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13
Q

radiationa nd cytotoxic drugs are

A

phatological apoptosis

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14
Q

cell breadown during menstruation is

A

physiological

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15
Q

when lymphocytes and monocytes die is

A

physiological

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16
Q

other name of monocytes

A

polymorphonuclears

17
Q

manifestations of metabolic derrangement in cells

A

intracellular accumulations

18
Q

where does intracellular accumulation happen

A

nucleus or cytoplasm

19
Q

due to genetic or acquired defects in metabolism, packaging, transport or secretion

A

normal and abnormal endogenous substance

20
Q

abnormal exogenous substances

A

deposited inside the cell and increase in number

21
Q

gives color

A

pigments

22
Q

example of lipids

A

triglycerides, cholesterol, cholesterol esthers, phospholipids

23
Q

abnormal accumualtions of triglycerides

A

steatosis or fatty change

24
Q

used by cell in the synthesis of cell membrane

A

cholesterol and cholesterol estherse

25
Q

round eosinopjilic droplets vacuoles or aggregates in the cytoplasm

A

proteins

26
Q

hyaline change

A

changes within cells or extracellular space

27
Q

where is glycogen stored

A

liver

28
Q

most common exogenous pigments

A

coal, carbon

29
Q

also known as the wear and tear pigment

A

lipofuscin

30
Q

melanin is derived from hemoglobin T or F

A

false

31
Q

main cause of lipofuscin accumualtion

A

cachexia or malnutrition

32
Q

ochronosis is seen in the accumulation of

A

hemogentisic acid

33
Q

black urine

A

alkaptonuria

34
Q

hemoglobin derived golden yellow to bron pigment

A

hemosiderin

35
Q

ferritin gives rise to

A

hemosiderin

36
Q

dpa or dihydroxyphenylalanin produced

A

tyrosine plus tyrosine catalase

37
Q

accumulation of iron in the liver

A

hemochromatosis

38
Q

normal major pigment in bile

A

billirubin

39
Q

PTH;CALCITONIN

A

BONE TO BLOOD: BLOOD TO BONE