cell necrosis Flashcards

1
Q

two types of cell death

A

apoptosis and necrosis

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2
Q

gross histologuc correlate of cell death

A

necrosis

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3
Q

what organelle causes cell death due to its enzymes

A

lysosomes

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4
Q

apoptosis always has inflammation

A

false

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5
Q

morphology od necrosis under microscope

A

increased eosinophilia, myelin figures, glassy homogenous figures, nucleu¥ar changes, calcification

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6
Q

develops presence of denaturation

A

coagulative necrosis

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7
Q

does not denote pattern of necrosis

A

fat necrosis

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8
Q

seen in the brain

A

liquefactive necrosis

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9
Q

cheesy white gross appearance

A

caseous necrosis

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10
Q

fat necrosis is due to

A

fat lipases

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11
Q

due to focal bacterial or fungal

A

liquefactive necrosis

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12
Q

induced by tightly regulated intracellular program

A

apoptosis

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13
Q

radiationa nd cytotoxic drugs are

A

phatological apoptosis

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14
Q

cell breadown during menstruation is

A

physiological

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15
Q

when lymphocytes and monocytes die is

A

physiological

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16
Q

other name of monocytes

A

polymorphonuclears

17
Q

manifestations of metabolic derrangement in cells

A

intracellular accumulations

18
Q

where does intracellular accumulation happen

A

nucleus or cytoplasm

19
Q

due to genetic or acquired defects in metabolism, packaging, transport or secretion

A

normal and abnormal endogenous substance

20
Q

abnormal exogenous substances

A

deposited inside the cell and increase in number

21
Q

gives color

22
Q

example of lipids

A

triglycerides, cholesterol, cholesterol esthers, phospholipids

23
Q

abnormal accumualtions of triglycerides

A

steatosis or fatty change

24
Q

used by cell in the synthesis of cell membrane

A

cholesterol and cholesterol estherse

25
round eosinopjilic droplets vacuoles or aggregates in the cytoplasm
proteins
26
hyaline change
changes within cells or extracellular space
27
where is glycogen stored
liver
28
most common exogenous pigments
coal, carbon
29
also known as the wear and tear pigment
lipofuscin
30
melanin is derived from hemoglobin T or F
false
31
main cause of lipofuscin accumualtion
cachexia or malnutrition
32
ochronosis is seen in the accumulation of
hemogentisic acid
33
black urine
alkaptonuria
34
hemoglobin derived golden yellow to bron pigment
hemosiderin
35
ferritin gives rise to
hemosiderin
36
dpa or dihydroxyphenylalanin produced
tyrosine plus tyrosine catalase
37
accumulation of iron in the liver
hemochromatosis
38
normal major pigment in bile
billirubin
39
PTH;CALCITONIN
BONE TO BLOOD: BLOOD TO BONE