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DOCTOR OF DENTAL MEDICINE 3 FIRST SEM MIDTERMS > CNS:ANTICONVULSANT > Flashcards

CNS:ANTICONVULSANT Flashcards

1
Q

Diverse groups of pharmocological agents used to treat epileptic seizures

A

anticonvulsants

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2
Q

sudden burs tof uncontrolled electrical activity that occurs in the brain when there is excessive activity

A

seizure

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3
Q

localized:
generalized:

A

one side of the brain: both sides of the brain

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4
Q

what is the mechanism of action of anticonvulsants

A
  1. blocks ion gated sodium and calcium channels
  2. inhibit action potential firing
  3. inhibit glutamate production
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5
Q

blocks both sodium and calcium channels

A

zonisamide, valproic acid, topiramate and lamotrigine

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6
Q

blocks sodium channels only

A

phenytoin, oxcarbazepine, carbamazepine

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7
Q

blocks 2 delta subunits

A

pregabalin, gabapentin

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8
Q

NMDA binds to

A

calcium

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9
Q

Sodium binds to

A

AMPA

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10
Q

blocks calcium channels

A

leviteracitam, felbamate, benzodiazepines, barbiturates, tiagabine, gigabatrin

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11
Q

blocks NMDA receptors

A

felbamate

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12
Q

it inhibits gaba reuptake

A

tiagabine

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13
Q

inhibits GABA transferase

A

vigabatrin

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14
Q

sedation and diziness is not common in anticonvulsant drugs, T or F

A

false

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15
Q

low sodium or hyponatremia is caused by what drugs

A

oxcarbazepine and carbamazepine

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16
Q

gingival hyperplasia and hirsutism is caused by what drug

A

phenytoin

17
Q

vigabatrin causes double vision T or F

A

F- loss of vision

18
Q

lamotrigine

A

double vision

19
Q

topiramate causes

A

weight loss

20
Q

weight gain and peripheral edema is caused by

A

valproic acid, gabapentin, and pregabalin

21
Q

topiramate and zonisamide causes

A

cognitive problems

22
Q

felbamate and valproic acid

A

liver toxicity

23
Q

NEUROLOGICAL DISORDER THAT RESULTS IN A PROGRESSIVE LOSS OF COORDINATION AND MOVEMENT

A

parkinsons disease

24
Q

sends dopamine to help coordinate brain inputs

A

substantia

25
Q

relays sensory information and plans for future action

A

neocortex

26
Q

responsible for movement

A

striatum

27
Q

precursor of dopamine

A

levodopa

28
Q

precursor of levodopa

A

tyroxine hydroxylase

DOCTOR OF DENTAL MEDICINE 3 FIRST SEM MIDTERMS (15 decks)

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