oncology midterms Flashcards

1
Q

enumerate the lesions under malignant non-odontogenic tumors

A

osteosarcoma, juxtacortical osteosarcoma (periosteal and parosteal), chondrosarcoma, burkitts lymphoma, ewings sarcoma, multiple myeloma, solitary plasmacytosis, metastatic carcinoma

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2
Q

the second most common malignancy of the bone

A

osteosarcoma

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3
Q

paresthesia is due to the

A

impingement of the inferior alveolar enrve1

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4
Q

maxillary osteosarcoma oresents the same pattern but may also cause:

A

impingement of ian, epistaxis, nasal obstruction, eye problems (proptosis and diplopia)

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5
Q

the most common subtype of osteosarcoma is

A

chondroblastic osteosarcoma

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6
Q

3 types of osteosarcoma based on the site of origin

A

conventional, juxtacortical, extraskeleteal

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7
Q

localized widening of the PDL space of one or two teeth

A

early osteosarcoma involving alveolar process

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8
Q

treatment of osteosarcoma includes

A

surgical management, chemotherapy, radical mandibullectomy, and maxillectomy

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9
Q

true or false osteosarcomas are more likely to metastaasize to the lungs, regional lymph nods and brain

A

true

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10
Q

t or f: parosteal is more common than periosteal

A

true

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11
Q

not covered by lining epithelium

A

parosteal osteosarcoma

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12
Q

common location of periosteal osteosarcoma

A

upper tibial metaphysis

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13
Q

common locatioon of parosteal osteosarcom

A

distal femoral metaphysic

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14
Q

long standing slow growing selling or palpable mass often accomanied by dull aching sensation

A

parosteal osteosarcoma

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15
Q

parosteal osteosarcoma can be mistakenly diagnosed as

A

gout

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16
Q

true or false: parosteal osteosarcoma has a more ossified base than periphery

A

false: more ossified periphery than base

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17
Q

radiographically is radiodense and is attached tot he external surface of bone

A

parosteal osteosarcoma

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18
Q

treatment for parosteal osteosarcoma

A

en bloc resection

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19
Q

covered by lining epithelium

A

periosteal osteosarcoma

20
Q

t or f females are more susceptible to periosteal osteosarcoma

A

false: males 2:1 ratio

21
Q

radiographic appearance of periosteal osteosarcoma

A

radiolucent

22
Q

a radiographic shadow between the raised ends of periosteum and cortical bone due to reactive bone formation

A

codmans triangle

23
Q

it is the third most common malignancy of the bone

A

chondrosarcoma

24
Q

location of chondrosarcoma in the maxilla

A

lateral incisor and canine region, and palate

25
location of chondrosarcoma in the mandible
premolar-molar region symphysis coronoid and condylar process
26
loosening of teeth and ill fitting dentures are clinical features of this lesion
chondrosarcoma
27
describe the histopathological grading of chondrosarcoma
grade 1; well differentiate, lobular grade 2: intermediate, myxoid stroma grade 3: poorly differentiated, spindle cell components
28
moth eaten radiolucency or diffusely opaque lesions unilocular or multilocular
chondrosarcomas
29
where does chondrosarcoma metastasize?
lungs and bone
30
other name of ewings sarcoma
primitive neuroectodermal tumor
31
etiology of ewings sarcoma
translocation of chromosomes 11 and 22
32
clinical features of ewings sarcoma
pain and swwlling and mucosal expansion facial deformitu and destruction of alvelar bone with loosening of teeth
33
salient histopathologic feature of ewings sarcoma is the presence of ________ which is stained by _________
glycogen; schiffs stain
34
may simulate infectious processes as well as malignant processes
ewing sarcoma
35
treatments for ewings
multiple method protocols surgery chemotherapy
36
translocation of the distal part of chromosomes 8-14
burkitts lymphoma
37
two forms if burkitts lymphma
endemic and sporadic
38
t or f: burkittls lymphoma is not curable
false: it is potentially curable
39
what are the 2 plasma cell neoplasm
multiple myeloma and solitary plasmacytoma of the bone
40
occurs spontaneously or when pt. are exposed to pesticide dioxin or ionizing radiation
multiple myeloma
41
most common location of pathologic fractures include
the spine, ribs and pelvis
42
a fracture caused by tumors
pathologic fractures
43
bence jones protein
multiple myeloma
44
standard treatment for multiple myeloma
melphalan and prednisone
45
patients in whome therapy is ineffective alternative drugs include
VBMCP= vincristine, carmustine, melpahalan, clorophosphamide, prednisone VAD= vincristine, adriamycine, dexamethasone
46
VBMCP AND VAD can cause
muscle weakness and increase chance of infectiosn
47