oncology midterms

Question 1

enumerate the lesions under malignant non-odontogenic tumors

Answer 1

osteosarcoma, juxtacortical osteosarcoma (periosteal and parosteal), chondrosarcoma, burkitts lymphoma, ewings sarcoma, multiple myeloma, solitary plasmacytosis, metastatic carcinoma

Question 2

the second most common malignancy of the bone

Answer 2

osteosarcoma

Question 3

paresthesia is due to the

Answer 3

impingement of the inferior alveolar enrve1

Question 4

maxillary osteosarcoma oresents the same pattern but may also cause:

Answer 4

impingement of ian, epistaxis, nasal obstruction, eye problems (proptosis and diplopia)

Question 5

the most common subtype of osteosarcoma is

Answer 5

chondroblastic osteosarcoma

Question 6

3 types of osteosarcoma based on the site of origin

Answer 6

conventional, juxtacortical, extraskeleteal

Question 7

localized widening of the PDL space of one or two teeth

Answer 7

early osteosarcoma involving alveolar process

Question 8

treatment of osteosarcoma includes

Answer 8

surgical management, chemotherapy, radical mandibullectomy, and maxillectomy

Question 9

true or false osteosarcomas are more likely to metastaasize to the lungs, regional lymph nods and brain

Answer 9

true

Question 10

t or f: parosteal is more common than periosteal

Answer 10

true

Question 11

not covered by lining epithelium

Answer 11

parosteal osteosarcoma

Question 12

common location of periosteal osteosarcoma

Answer 12

upper tibial metaphysis

Question 13

common locatioon of parosteal osteosarcom

Answer 13

distal femoral metaphysic

Question 14

long standing slow growing selling or palpable mass often accomanied by dull aching sensation

Answer 14

parosteal osteosarcoma

Question 15

parosteal osteosarcoma can be mistakenly diagnosed as

Answer 15

gout

Question 16

true or false: parosteal osteosarcoma has a more ossified base than periphery

Answer 16

false: more ossified periphery than base

Question 17

radiographically is radiodense and is attached tot he external surface of bone

Answer 17

parosteal osteosarcoma

Question 18

treatment for parosteal osteosarcoma

Answer 18

en bloc resection

Question 19

covered by lining epithelium

Answer 19

periosteal osteosarcoma

Question 20

t or f females are more susceptible to periosteal osteosarcoma

Answer 20

false: males 2:1 ratio

Question 21

radiographic appearance of periosteal osteosarcoma

Answer 21

radiolucent

Question 22

a radiographic shadow between the raised ends of periosteum and cortical bone due to reactive bone formation

Answer 22

codmans triangle

Question 23

it is the third most common malignancy of the bone

Answer 23

chondrosarcoma

Question 24

location of chondrosarcoma in the maxilla

Answer 24

lateral incisor and canine region, and palate

Question 25

location of chondrosarcoma in the mandible

Answer 25

premolar-molar region
symphysis
coronoid and condylar process

Question 26

loosening of teeth and ill fitting dentures are clinical features of this lesion

Answer 26

chondrosarcoma

Question 27

describe the histopathological grading of chondrosarcoma

Answer 27

grade 1; well differentiate, lobular
grade 2: intermediate, myxoid stroma
grade 3: poorly differentiated, spindle cell components

Question 28

moth eaten radiolucency or diffusely opaque lesions unilocular or multilocular

Answer 28

chondrosarcomas

Question 29

where does chondrosarcoma metastasize?

Answer 29

lungs and bone

Question 30

other name of ewings sarcoma

Answer 30

primitive neuroectodermal tumor

Question 31

etiology of ewings sarcoma

Answer 31

translocation of chromosomes 11 and 22

Question 32

clinical features of ewings sarcoma

Answer 32

pain and swwlling and mucosal expansion
facial deformitu and destruction of alvelar bone with loosening of teeth

Question 33

salient histopathologic feature of ewings sarcoma is the presence of ________ which is stained by _________

Answer 33

glycogen; schiffs stain

Question 34

may simulate infectious processes as well as malignant processes

Answer 34

ewing sarcoma

Question 35

treatments for ewings

Answer 35

multiple method protocols
surgery
chemotherapy

Question 36

translocation of the distal part of chromosomes 8-14

Answer 36

burkitts lymphoma

Question 37

two forms if burkitts lymphma

Answer 37

endemic and sporadic

Question 38

t or f: burkittls lymphoma is not curable

Answer 38

false: it is potentially curable

Question 39

what are the 2 plasma cell neoplasm

Answer 39

multiple myeloma and solitary plasmacytoma of the bone

Question 40

occurs spontaneously or when pt. are exposed to pesticide dioxin or ionizing radiation

Answer 40

multiple myeloma

Question 41

most common location of pathologic fractures include

Answer 41

the spine, ribs and pelvis

Question 42

a fracture caused by tumors

Answer 42

pathologic fractures

Question 43

bence jones protein

Answer 43

multiple myeloma

Question 44

standard treatment for multiple myeloma

Answer 44

melphalan and prednisone

Question 45

patients in whome therapy is ineffective alternative drugs include

Answer 45

VBMCP= vincristine, carmustine, melpahalan, clorophosphamide, prednisone
VAD= vincristine, adriamycine, dexamethasone

Question 46

VBMCP AND VAD can cause

Answer 46

muscle weakness and increase chance of infectiosn