Oncology I

Question 1

What are the 7 signs of cancer?

Answer 1

CAUTION

1. change in bowl or bladder habits
2. a sore that does not heal
3. unusual bleeding or discharge
4. thickening or lump in breast or elsewhere
5. indigestion or difficulty swallowing
6. obvious change in wart or mole
7. nagging cough or hoarseness

Question 2

What are the three types of skin cancer?

Answer 2

basal cell, squamous cell, and melanoma

Question 3

How to prevent skin cancer?

Answer 3

seek shade, slip on a shirt, sunscreen, hat, sunglasses

Question 4

What is ABCDE?

Answer 4

asymmetry, border, color, diameter, evolving

Question 5

Adjuvant?

Answer 5

therapy after primary therapy

Question 6

Neoadjuvant?

Answer 6

therapy given before surgery

Question 7

What are common SE of most chemo regimen?

Answer 7

diarrhea, alopecia, myelosuppression

Question 8

What is the max dose of bleomycin and why?

Answer 8

lifetime 400 units b/c pulmonary toxicity

Question 9

What is the max dose of doxorubicin and why?

Answer 9

lidetime 450-550 mg/m2 b/c cardiotoxicity

Question 10

what is the max dose of cisplatin and why?

Answer 10

dose per cycle not exceed 100 mg/m2 b/c nephrotoxicity

Question 11

what is the max dose of vincristine and why?

Answer 11

single dose “capped” at 2 mg b/c neuropathy

Question 12

Which drugs do not cause myelosuppression

Answer 12

bleomycin, vincristine, TKIs

Question 13

Drugs more likely emetogenic?

Answer 13

cisplatin

Question 14

Drugs likely to cause mucositis?

Answer 14

fluorouracil, capecitabine, irinotecan, methotrexate

Question 15

Drugs likely to cause diarrhea?

Answer 15

fluorouracil, capecitabine, irinotecan, TKI

Question 16

Drugs likely to cause constipation?

Answer 16

vincristine, pomalidomide, thalidomide

Question 17

What is mesna used for?

Answer 17

ifosfaamide and cyclophosphamide

Question 18

Drugs likely to cause neuropathy?

Answer 18

vinca alkaloids, platinums, taxanes

Question 19

When does myelosuppression happen?

Answer 19

7-14 days

Question 20

Neulasta

Answer 20

pegfilgrastim

Question 21

Leukine

Answer 21

sargramostim

Question 22

Ethyol

Answer 22

amifostine

Question 23

what is ethyol used for?

Answer 23

nephrotoxic prophylaxis from cisplatin

Question 24

Fusilev

Answer 24

leucovorin

Question 25

Vistogard

Answer 25

uridine triacetate

Question 26

What is vistogard used for?

Answer 26

antidote used within 96 hours for fluorouracil or capecitabine

Question 27

Voraxaze

Answer 27

glucarpidase

Question 28

neupogen, Zarxio

Answer 28

filgrastim

Question 29

Granix

Answer 29

tbo-filgrastim

Question 30

When to administer CSF?

Answer 30

24 hours after chemo

Question 31

Examples of NK 1-RA?

Answer 31

Aprepitant, fosaprepitant, rolapitant

Question 32

Emend

Answer 32

Aprepitant, fosaprepitant

Question 33

Akynzeo

Answer 33

netupitant and palonosetron

Question 34

Varubi

Answer 34

rolapitant

Question 35

Zofran, zuplenz

Answer 35

ondansetron

Question 36

Kytril, Sancuso, Sustol

Answer 36

granisetron

Question 37

Anzement

Answer 37

dolasetron

Question 38

Aloxi

Answer 38

palonosetron

Question 39

Examples of Dopamine antagonists

Answer 39

prochlorperazine, promethazine, metoclopramide, droperidol

Question 40

Compazine, compro

Answer 40

prochlorperazine

Question 41

Phenergan, Phenadoz, Promethegan

Answer 41

promethazine

Question 42

Reglan

Answer 42

metoclopramide

Question 43

Cesamet

Answer 43

nabilone

Question 44

Salagen

Answer 44

pilocarpine