Oncology I Flashcards

(44 cards)

1
Q

What are the 7 signs of cancer?

A

CAUTION

  1. change in bowl or bladder habits
  2. a sore that does not heal
  3. unusual bleeding or discharge
  4. thickening or lump in breast or elsewhere
  5. indigestion or difficulty swallowing
  6. obvious change in wart or mole
  7. nagging cough or hoarseness
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2
Q

What are the three types of skin cancer?

A

basal cell, squamous cell, and melanoma

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3
Q

How to prevent skin cancer?

A

seek shade, slip on a shirt, sunscreen, hat, sunglasses

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4
Q

What is ABCDE?

A

asymmetry, border, color, diameter, evolving

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5
Q

Adjuvant?

A

therapy after primary therapy

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6
Q

Neoadjuvant?

A

therapy given before surgery

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7
Q

What are common SE of most chemo regimen?

A

diarrhea, alopecia, myelosuppression

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8
Q

What is the max dose of bleomycin and why?

A

lifetime 400 units b/c pulmonary toxicity

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9
Q

What is the max dose of doxorubicin and why?

A

lidetime 450-550 mg/m2 b/c cardiotoxicity

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10
Q

what is the max dose of cisplatin and why?

A

dose per cycle not exceed 100 mg/m2 b/c nephrotoxicity

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11
Q

what is the max dose of vincristine and why?

A

single dose “capped” at 2 mg b/c neuropathy

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12
Q

Which drugs do not cause myelosuppression

A

bleomycin, vincristine, TKIs

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13
Q

Drugs more likely emetogenic?

A

cisplatin

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14
Q

Drugs likely to cause mucositis?

A

fluorouracil, capecitabine, irinotecan, methotrexate

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15
Q

Drugs likely to cause diarrhea?

A

fluorouracil, capecitabine, irinotecan, TKI

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16
Q

Drugs likely to cause constipation?

A

vincristine, pomalidomide, thalidomide

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17
Q

What is mesna used for?

A

ifosfaamide and cyclophosphamide

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18
Q

Drugs likely to cause neuropathy?

A

vinca alkaloids, platinums, taxanes

19
Q

When does myelosuppression happen?

20
Q

Neulasta

A

pegfilgrastim

21
Q

Leukine

22
Q

Ethyol

23
Q

what is ethyol used for?

A

nephrotoxic prophylaxis from cisplatin

24
Q

Fusilev

25
Vistogard
uridine triacetate
26
What is vistogard used for?
antidote used within 96 hours for fluorouracil or capecitabine
27
Voraxaze
glucarpidase
28
neupogen, Zarxio
filgrastim
29
Granix
tbo-filgrastim
30
When to administer CSF?
24 hours after chemo
31
Examples of NK 1-RA?
Aprepitant, fosaprepitant, rolapitant
32
Emend
Aprepitant, fosaprepitant
33
Akynzeo
netupitant and palonosetron
34
Varubi
rolapitant
35
Zofran, zuplenz
ondansetron
36
Kytril, Sancuso, Sustol
granisetron
37
Anzement
dolasetron
38
Aloxi
palonosetron
39
Examples of Dopamine antagonists
prochlorperazine, promethazine, metoclopramide, droperidol
40
Compazine, compro
prochlorperazine
41
Phenergan, Phenadoz, Promethegan
promethazine
42
Reglan
metoclopramide
43
Cesamet
nabilone
44
Salagen
pilocarpine