Oncology I Flashcards
(44 cards)
What are the 7 signs of cancer?
CAUTION
- change in bowl or bladder habits
- a sore that does not heal
- unusual bleeding or discharge
- thickening or lump in breast or elsewhere
- indigestion or difficulty swallowing
- obvious change in wart or mole
- nagging cough or hoarseness
What are the three types of skin cancer?
basal cell, squamous cell, and melanoma
How to prevent skin cancer?
seek shade, slip on a shirt, sunscreen, hat, sunglasses
What is ABCDE?
asymmetry, border, color, diameter, evolving
Adjuvant?
therapy after primary therapy
Neoadjuvant?
therapy given before surgery
What are common SE of most chemo regimen?
diarrhea, alopecia, myelosuppression
What is the max dose of bleomycin and why?
lifetime 400 units b/c pulmonary toxicity
What is the max dose of doxorubicin and why?
lidetime 450-550 mg/m2 b/c cardiotoxicity
what is the max dose of cisplatin and why?
dose per cycle not exceed 100 mg/m2 b/c nephrotoxicity
what is the max dose of vincristine and why?
single dose “capped” at 2 mg b/c neuropathy
Which drugs do not cause myelosuppression
bleomycin, vincristine, TKIs
Drugs more likely emetogenic?
cisplatin
Drugs likely to cause mucositis?
fluorouracil, capecitabine, irinotecan, methotrexate
Drugs likely to cause diarrhea?
fluorouracil, capecitabine, irinotecan, TKI
Drugs likely to cause constipation?
vincristine, pomalidomide, thalidomide
What is mesna used for?
ifosfaamide and cyclophosphamide
Drugs likely to cause neuropathy?
vinca alkaloids, platinums, taxanes
When does myelosuppression happen?
7-14 days
Neulasta
pegfilgrastim
Leukine
sargramostim
Ethyol
amifostine
what is ethyol used for?
nephrotoxic prophylaxis from cisplatin
Fusilev
leucovorin
