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NAPLEX > CH. 46 migraine > Flashcards

CH. 46 migraine Flashcards

1
Q

What are the phases of migraine

A

vulnerability –> prodrome (24h) –> Aura (1h) –> Headache (3 hours to days) –> Post headache state

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2
Q

What are possible causes of migraine?

A

vasodilation of the cranial blood vessels, hyper-excitable neurons, genetic, women > men

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3
Q

Common migraine triggers?

A

Hormonal changes, food (alcohol, MSG, red wine, aged cheese) stress, sensory stimuli, changes in sleep-wake pattern, changes in environment

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4
Q

Natural products for migraine

A

Butterbur, Coenzyme Q10, feverfew, magnesium, peppermint (topically), riboflavin

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5
Q

MOA of triptans

A

selective 5-HT1 receptor agonists and cause vasoconstriction of cranial blood vessels

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6
Q

Amerge

A

naratriptan

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7
Q

Axert

A

Almotriptan

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8
Q

Frova

A

Frovatriptan

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9
Q

Imitrex, sumavel, Zembrace, Onzetra xsail

A

sumatriptan

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10
Q

Maxalt

A

rizatriptan

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11
Q

Relpax

A

eletriptan

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12
Q

Zomig

A

zolmitriptan

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13
Q

What is the oldest triptan?

A

sumatriptan

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14
Q

Treximet

A

sumatriptan and naproxen

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15
Q

Which triptan are ODT?

A

rizatriptan and zolmitriptan

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16
Q

Which triptan have a PED indication?

A

almotriptan, zolmitriptan nasal spray, treximet > 12 and rizatriptan > 6

17
Q

Migranal and D.H.E

A

dihydroergotamine

18
Q

Cafergot and Migergot

A

Ergotamine and caffeine

19
Q

MOA of ergotamine

A

nonselective agonist of serotonin receptors causing vasoconstriction

20
Q

Type of medication used for prophylactic treatment?

A

antihypertensives 9BB), Antiepileptic, antidepressants, oral contraceptive, botox

21
Q

Indreal LA

A

propranolol

22
Q

Lopressor, toprol XL

A

metoprolol

23
Q

BB used for migraine

A

propranolol, timolol, metoprolol

24
Q

Antiepileptic drugs used for migraine?

A

Topiramate, valproic acid

25
Q

Depakote

A

divalproex

26
Q

Depakene

A

valproic acid

27
Q

Topamax, Trokendi XR

A

topiramate

28
Q

Antidepressents for migraine

A

amitriptyline, venlafaxine

NAPLEX (13 decks)

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