Oncology Flashcards

1
Q

1 cause of of preventable cancer

A

tobacco

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2
Q

Risk factors for Cancer

A
  • Alcohol + tobacco = Co-carcinogenic
  • Low fiber, ↑red meat, ↑animal fat, Nitrites (processed sandwich meats), alcohol, preservatives and additives
  • Obesity
  • Immunosuppressed
  • Aging (>60)
  • African Americans → Caucasians
  • Heredity
  • exposure to UV-radiation and carcinogens
  • Stress
  • Chronic irritation = uncontrolled growth of abnormal cells
  • Previous medical hx of other types of cancer or chemotherapy
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3
Q

Cancer Primary prevention

A
  • No smoking
  • exercise and good nutrition
  • maintain normal body wt
  • limit/eliminate alcohol
  • Hep B and HPV vaccines
  • avoid exposure to known carcinogens - wear suncreen, avoid prolong sun exposure, avoid 2n-hand smoke
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4
Q
Cancer Secondary prevention 
FEMALES
• BSE?
• Clinical breast exams?
• Mammogram? Teaching?
• Pap smear?
• Colonoscopy?
• fecal occult blood test?
A

• beginning in 20’s - monthly breast self-exams (BSE)
- day 7 - day 12; or same day every month
• 40 yo - Yearly clinical breast exams; 20 - 39 yo once every 3 yrs
• 40 yo - Mammogram; DO NOT apply lotion/powder/deodorant beforehand
• at 21, start Pap Smear then every 3 yrs
• at 50, Colonoscopy - then every 10 yrs
• at 50, testing stool for fecal occult blood YEARLY

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5
Q
Cancer Secondary prevention 
MALES
• Clinical Testicular exams?
• TSE?
• digital rectal exam, prostate specific antigen (PSA)?
• colonoscopy?
• fecal occult blood test?
A

• info about breast self-awareness
• Yearly clinical testicular exams
- Monthly testicular self-exams (TSE); testicular cancer common in age group of 15-36 yo
• >50 - digital rectal exam and prostate-specific antigen (PSA)
• at 50, Colonoscopy then every 10 yrs
• at 50, testing stool for fecal occult blood YEARLY

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6
Q

Cancer Tertiary prevention

A
  • support groups

* rehabilitation programs

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7
Q

General S/SX of Cancer?

• What’s C.A.U.T.I.O.N.?

A
Change in bowel/bladder habits
A sore that does not heal
Unusual bleeding/discharge
Thickening or lump in breast/elsewhere
Indigestion or difficulty swallowing
Obvious change in wart/mole
Nagging cough or hoarseness
  • anemia, leukopenia, thrombocytopenia
  • Unexplained weight loss (CACHEXIA: extreme wasting and malnutrition)
  • Fever
  • FATIGUE - #1 Symptom (doesn’t get better w/ sleep)
  • Pain
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8
Q

Cancer:

Bleeding Precautions

A
  • Use an electric razor
  • Use a soft toothbrush
  • No IMs
  • Quiet play for children
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9
Q

Cancer:

Blood Tests

A
  • Abnormal CBC and diff - Always worry about NEUTROPHIL COUNT (normal: 2500-8000)
  • ↑ AST and ALT
  • tumor biomarkers
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10
Q

Cancer:

Positive Diagnostic Studies

A
CXR
CT
MRI
PET Scan
Bone marrow biopsy
Tissue biopsy
Imaging studies
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11
Q

Cancer:

Surgery is used for?

A

Prevention - removing benign tumor
Diagnosis - staging, biopsy, lymph node mapping
Treatment

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12
Q

Curative Surgery: Tx for laryngeal cancer?

A

Total laryngectomy (removal of VOCAL cords, epiglottis, thyroid cartilage)

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13
Q

TOTAL LARYNGECTOMY
• This client will have a permanent what?
• Position post-op?
• NG feedings to protect what? why it’s used?
• Monitor what?
• Watch for ____ artery rupture = MEDICAL EMERGENCY-CALL PROVIDER
• Rupture of the _____ artery = go to OR ASAP!
• Frequent ____ care to decrease bacterial count in mouth
• NPO people tend to get ____
• When the client leaves the hospital, what will be used to cover trach and acts like a filter?
• A _____ environment helps
• All breathing is done thru the ____
• How does a client w/ total laryngectomy talk?
• DONT’s of total laryngectomy

A
  • Permanent tracheostomy or laryngectomy
  • Position - MID FOWLERS
  • NG feedings to protect SUTURE LINE because PERISTALSIS can disrupt it
  • Monitor DRAINS
  • Watch for CAROTID artery rupture = MEDICAL EMERGENCY-CALL PROVIDER
  • Rupture of the INNOMINATE artery = go to OR ASAP!
  • Frequent ORAL care to decrease bacterial count in mouth
  • NPO people tend to get PNEUMONIA
  • BIB will be used to cover trach and acts like a filter?
  • A HUMIDIFIED environment helps
  • All breathing is done thru the STOMA
  • A client w/ total laryngectomy talk with an electrolarynx or the BLOM-SINGER DEVICE
  • NO WHISTLING, NO DRINKING THRU STRAW; SMOKING AND SWIMMING NOT RECOMMENDED
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14
Q

Reconstructive Surgery: Tx for breast cancer?

A

Mastectomy - partial or total (radical)

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15
Q

MASTECTOMY Post-Op Care
• Bleeding–what to check?
• if reconstruction includes using their own tissue, they will also have an ____ surgical site
• what type of drains will they have?

A
  • Check dressings, front and back (pooling of blood can occur)
  • they will also have an ABDOMINAL surgical site (most common site to harvest adipose tissue)
  • Hemovac or Jackson-Pratt drains
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16
Q

MASTECTOMY Nursing Care (if lymph nodes also removed)

• Brush hair, squeeze tennis balls, wall climbing, flex and extend elbow. Why?

A
  • NO CONSTRICTION
  • no BPs
  • no blouses w/ elastic
  • no watch
  • no IV or injections on affected side
  • wear gloves when gardening
  • watch small cuts
  • no nail biting
  • no sunburn

• Promotes NEW (collateral) circulation

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17
Q

Internal Radiation
• Use?
• it’s internal radiation, so it’s ____ the body
• w/ all types, the client emits ____ for a period of time and is a hazard to others
• Unsealed?
• Sealed/Solid? Examples?

A

(BRACHYTHERAPY)
• Used to get the radiation close to the cancer or target tissue
• it’s INSIDE the body
• client emits RADIATION
• Unsealed (client and body fluids emit radiation); IV or PO; Radioactive for 24-48 hrs
• Sealed/Solid (client emits radiation, not body fluids_; temporary or permanent implant placed close to or inside tumor
—Examples: Implantable seeds (prostate ca); vaginal implant (cervical ca)

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18
Q

Precautions w/ Internal Radiation (BRACHYTHERAPY)
• Nursing assignments should be rotated ____, so the nurse is not continuously exposed.
• Nurse should only care for ____ client w/ a radiation implant in a given shift
• Placed in a ____ room? why?
• Wear ____ at all times
• Time limit for visitors? Distance from source? No visitors for ages less than what? No ____ visitors/nurses
• Mark the room w/ instruction for what?
• wear ____ w/ risk of exposure to body fluids
• Prevent dislodgement of the implant by: Keep client on ____, Decrease ____ in diet, Prevent bladder ____
• What do you do if the implant becomes dislodged and you see it?
• Teaching for client?

A

• Nursing assignments rotated DAILY
• Only care for ONE client w/ radiation implant
• PRIVATE room coz client is IMMUNOSUPPRESSED
• wear FILM BADGE at all times
• only 30 MINUTES per day; at least 6 FEET from source; No visitors <16 yo; No PREGNANT visitors/nurses
• Mark the room w/ instruction for SPECIFIC ISOTOPE
• Wear GLOVES w/ risk of exposure to body fluids
• Prevent dislodgement of the implant by: Keep client on BED REST, Decrease FIBER in diet, Prevent bladder DISTENTION
• dislodged implant - Gloves → Use forceps to pick up dislodged implant → Place implant in a lead-lined container → leave in room, call radiation department
• Teaching:
–After radiation, NO SLEEPING in the same bed w/ spouse or children
–NO USE of public transportation
–NO to returning to work immediately
–NO SHARING of utensils or cooking for others
–After us, close lid then flush toilet 2-3 times

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19
Q
External Radiation
• use?
• client radioactive or not?
• Side Effects?
• s/sx are \_\_\_\_ and \_\_\_\_ related
• Teaching for client?
A

Teletherapy/External Beam Radiotherapy
• A carefully focused beam of high energy rays is delivered by a machine OUTSIDE of the body
• client is NOT RADIOACTIVE
• SE: erythema, shedding of skin, FATIGUE, Pancytopenia
• s/sx are LOCATION and DOSE related
• Teaching:
–NO WASHING OFF markings
–NO USING LOTION on markings
–Protect site from sunlight and UV exposure for 1 YEAR
–Good skin care; NO LOTION/POWDER/OINTMENT w/o PHP order

20
Q

Action of Chemotherapy
• goal?
• Specific chemo drugs? Non-specific chemo drugs?
• work best when?

A

• Goal - ELIMINATE/REDUCE number of cancer cells by destroying cells as they’re developing
• Specific - attack a specific phase of cell development
Non-Specific - work at all/any phase of cell development
• Work best when cells are ACTIVELY GROWING
*most active growth is when tumor first begins to develop

21
Q

Precautions for administration of Chemotherapy
• Routes?
• Be careful, why?
• make sure you are ____ it correctly
• Exposure can occur by drug contact with the what?

A
  • Routes: oral, topical, IM, IV, intracavity (directly into body cavity)
  • Be careful because of Exposure to drugs that are CARCINOGENIC, MUTAGENIC, TERATOGENIC
  • make sure you are HANDLING it correctly
  • Exposure can occur by drug contact with the SKIN or MUCOUS MEMBRANES, INHALATION, INGESTION, ACCIDENTAL INJECTION
22
Q

Chemotherapy Full precautions require
• gown? coated why? what to do if contaminated?
• gloves? placement?
• goggles/mask?

A
  • Chemotherapy gown; coated to prevent contamination; change immediately if contaminated
  • 2 PAIRS chemotherapy gloves (thicker, longer); one pair under gown, one pair over the gown cuff
  • Goggles and/or mask if there’s splashing/inhalation
23
Q

Chemo drugs can be given orally. Wear ____ with administration

A

Chemotherapy gloves

24
Q

Chemotherapy: Excretion precautions
• what to wear when handling body fluids?
• chemotherapy is excreted when?

A
  • 2 pairs of chemo gloves and chemo gown

* 3 - 7 days after administration

25
Disposal of Chemotherapy
* Yellow rigid chemo waste container (sharps, IV equipment) * Yellow chemo waste bag (gowns, gloves, disposable items) * wash hand w/ soap and water after removing gloves
26
Chemotherapy: Managing Spills
* hHandle as a HAZARDOUS CHEMICAL SPILL * Obtain Spill Kit and use ALL protective equipment for clean up --wash hands w/ soap and water → get SPILL KIT → Post "Caution Chemo spill" sign outside the room door → resp mask → chemo gown → 2 chemo gloves → goggles →ise absorbent pads to wipe up spill
27
EXTRAVASATION • Patho? • S/SX • Treatment?
Complication w/ Chemotherapy Administration • Chemo drugs are given in a central IV line; Peripheral line only if IV push or infusion <1 hr; VESICANT (chemo drug that if it infiltrates = NECROSIS) • s/sx: Pain, Swelling, No blood return • Tx #1 thing to remember - PREVENTION! STOP INFUSION and send for extravasation kit → stay w/ client and watch the site
28
Transplants • use for? • Stem cells from blood or bone marrow can come from where? • Stem cells are given into ____ much like a blood transfusion → over time, settle in the bone marrow = produce ____ ____ cells
* Treatment for HEMATOLOGIC cancers * Stems cells come from the client, a matched donor, or identical sibling/twin * Stem cells are given into VEIN → over time, settle in the bone marrow = produce HEALTHY BLOOD cells
29
Stem Cell Transplant
stems cells are transplanted from bloodstream
30
Bone Marrow Transplant
stem cells are transplanted from bone marrow
31
Transplant: Early signs of rejection
``` abdominal pain jaundice pruritus diarrhea dark, tea colored urine (RBC breakdown) ```
32
SE of Cancer and/or Cancer Tx | GI System
1) Nausea/Vomiting (N/V) • last 24-48 after tx • routine antiemetic meds given 1st week of chemo TREATMENT: Antiemetic drugs 1. ondansetron (Zofran) -serotonin receptor antagonists (-tron): onsansetron, granisetron, dolasetron 2.Netupitant/palonosetron (Akynzeo) -oral combination antiemetic; prevents acute and delayed N/V from chemo -- 1 dose 1 pill 1 hr before chemo 3. Non-pharmacologic tx -Ginger -Aromatherapy -acupuncture, acupressure, distraction and relaxation techniques (music therapy, peppermint essential oil diffuser) 2) Stomatitis oral cavity susceptible to irritation 3) Diarrhea worry nutrition and FE imbalances
33
SE of Cancer and/or Cancer Tx | Integumentary System
• alopecia (hair loss) • sense of loss w/ mastectomy, amputation, surgery scar ---have them look at the incision
34
SE of Cancer and/or Cancer Tx Hematopoietic System (Bone Marrow) • what's #1 cause of cancer-related deaths?
* ↓ RBCs, ↓ WBCs, ↓ Platelets -- client at risk for anemia, infection, and bleeding * INFECTION is #1 cause of cancer-related deaths
35
``` General Precautions to Prevent Infection • what type of room? limit what? • keep what in the room? what items not to share? • what needs to be changed daily? • how to prevent pneumonia? • gardening and cleaning? • being in public? • what to do frequently? • what to do after touching a pet? • drink what? • avoid what in diet? • brush teeth with? how often? • mouthwash? • report to hospital if? ```
* Private room; Limit visitors and nurses in the room * Keep client's own supplies; Don't share toiletries * Change dressings and IV tubing daily * Cough and deep breathe to prevent pneumonia * NO gardening or cleaning up after pets * Avoid crowds; Wear mask when out in public * Good handwashing frequently using antibacterial gel * Wash hands after touching a pet * Drink FRESH WATER * Avoid uncooked meat, seafood, eggs (No sushi); Avoid fresh/raw fruits/vegetables * Brush teeth w/ SOFT toothbrush 4 TIMES daily * NO alcohol-based mouthwash * report to hospital for temp >100.4 (38 C)
36
``` Neutropenic Precautions (+general precautions) • what's prescribed? • VS every how many hours? • what type of room? • what soap to use for handwashing? • what procedures to avoid? • what to avoid if at all possible • limit use of what med? ```
* Antibiotics as prescribed * VS q4h (temp check q2h) * Private room w/ door closed and posted sign * Antimicrobial soap for handwashing (not regular soap_ * No invasive procedures (IM injections, rectal exams/meds) * Avoid indwelling catheters and NG tubes * limit use of acetaminophen (Tylenol)
37
SE of Cancer and/or Cancer Tx FATIGUE • treatment?
* every onc client has some fatigue, some d/t tx | * provide period rest, naps, limit visitation time; teach clients to do these at home
38
SE of Cancer and/or Cancer Tx PAIN • Treat pain without worry about risk for ____ • Causes of pain? • "Gold standard" treatment for pain? imp info to remember?
• Treat pain without worry about risk for DEPENDENCE • causes of pain - direct tumor involvement, result of tx (mucositis, peripheral neuropathy) • OPIOIDS is gold standard tx --NO ceiling on dose for a cancer client; Limit dose coz of SE, not dose/time; Call PHP if increased dose needed
39
Complementary/Alternative therapies for Pain Management
* Acupressure * Acupuncture * Cannabis (Marijuana) * Distraction therapies (music, peppermint essential oil diffuser) * Hydrotherapy * Massage
40
NEUTROPENIA • what is it? • normal ANC? • treatment?
* ↓ neutrophils (mature WBCs) in blood * 2500 - 8000 cells/mm * Tx: Antibiotics; Implement Neutropenic Precautions
41
DVT's • Why is cancer a big risk factor for development of a DVT? • What are we most afraid of w/ DVT?
* Prolonged bed rest; Surgery; Use of central line; External compression of vessels by tumor; Invasion of cells by tumor; Certain chemo drugs * Worry about development of a PE (Pulmonary embolus)
42
``` THROMBOCYTOPENIA • what is it? Platelets responsible for what? • risk factors? • assessment? • treatment? ```
• ↓ of circulating platelets in blood; Platelets responsible for clotting (must have platelets to clot the blood to prevent bleeding) RISK FACTORS • advanced metastatic disease • hematological malignancies • bleeding disorders (Hemophilia, liver disease, ITP) • bacterial infections • Anticoagulant meds - aspirin, clopidogrel (Plavix), Heparin, warfarin (Coumadin) • result of cancer tx ``` ASSESSMENT • History • VS • O2 sats • Change in LOC (headache, pupil changes) • conjunctival hemorrhages • petechiae, ecchymosis, purpura • oozing from puncture/surgical sites • bleeding from rectum, ears, nose, or mouth ``` TREATMENT • Give platelets
43
Blood products • RBC transfusions • Platelet transfusions • Why are blood products irradiated?
* RBC for clients w/ symptomatic anemia--don't want H/H to drop below 8 g/dL and 24% (need RBCs) * PLT - control or prevent bleeding in thrombocytopenia * Reduces risk of transfusion-related reactions
44
``` Blood Product Infusion Process POINTS TO REMEMBER • administered by who? • what IV solution to use • what NOT to infuse via blood IV tubing • all blood products require what? • blood will be given via ____ • what needs to be done before administering the blood? ``` * each client must have _____ in the lab prior to obtaining a blood product; it's only good for how many hours? * Verification - where? with who? what to verify? * Check blood product, why? * What do you need prior to administering blood or blood products? * STEPS of infusion * do NOT infuse blood quickly in what clients? * infusion should be started within ____ minutes of receiving blood from blood bank * all blood from each unit must be completed within a ____ hour time frame
* administered by RN * Only use NS * do NOT infuse meds via blood IV tubing * need a filter * given via pump * baseline VS and transfusion records, 2 IVs * each client must have TYPE and SCREEN and CROSSMATCH in the lab prior to obtaining a blood product; it's only good for 72 HOURS * 1) in the blood blank and on the floor; 2) w/ a designated person in blood bank and w/ another RN at the bedside on the floor; 3) client's name, DOB, blood bank #, unit #, exp date of unit of blood/blood product, blood type and group, PHP's prescription * check for any signs of abnormalities * PHP's prescription and client's signed consent form (PHP's responsibility to explain need and possible SE) STEPS of infusion • 2 IVs ready → baseline VS → get blood from blood bank → Started within 30 mins of receiving blood from blood bank → Begin infusion SLOWLY → obser client for first 15 mins → no reaction, ↑infusion rate (must be completed within 4 HOURS) → dispose blood tubing and blood/blood product bag → flush lines w/ 0.9 NS after transfusion → Document * do NOT infuse blood quickly in -- elderly, has heart or kidney condition, or very young * infusion should be started within 30 MINUTES of receiving blood from blood bank * completed within 4 HOURS
45
Blood Product Infusion Process | SIGNS OF TRANSFUSION REACTION
* chest pain * hives or skin rash * hypotension/hypertension * fever * chills * anxiety * wheezing * headache or muscle pain w/ fever * flushing * back pain * dizziness * itching * urticaria * tachycardia * tachypnea * dyspnea * N/V
46
Blood Product Infusion Process | If an adverse reaction occurs you should:
* STOP INFUSION * remove blood and blood tubing set * may have to return blood and tubing to blood bank * start NS w/ new primed tubing at keep vein open (KVO) rate * check and document VS--stay w/ client * notify PHP and monitor for anaphylaxis * notify lab/blood bank of reaction