Oncology

Question 1

Cytotoxic drug that may cause myelosuppression, mucositis, liver fibrosis, lung fibrosis

Answer 1

Methotrexate

Question 2

Cytotoxic drug that may cause peripheral neuropathy (reversible) , paralytic ileus

Answer 2

Vincristine

Question 3

Cytotoxic drug that may cause nephrotoxicity, ototoxicity, peripheral neuropathy, hypomagnesaemia

Answer 3

Cisplatin

Question 4

BRCA2 mutation is associated with which cancer in men

Answer 4

Breast and prostate

Question 5

Indicators of poor prognosis in Hodgkin’s lymphoma

Answer 5

Lymphocyte depleted subtype or B symptoms

Question 6

Treatment for non-small cell lung cancer and for small cell lung cancer:

Answer 6

Non-small: surgery if local.
Small cell: chemo-radio.