OHCEPS - The Abdomen Flashcards
Principal symptom of esophageal disease?
Dysphagia
Dysphagia - what to know?
- Level of obstruction
- Onset
- Course
- Solids/Liquids
- Associated symptoms
Course of dysphagia?
- Intermittent?
- Present for only the first few shallows (lower esophageal ring, spasm)?
- Progressive (cancer, stricture, achalasia)?
Dysphagia - associates symptoms?
- Heartburn –> leads to esophageal strictures.
- Weight loss, wasting, fatigue –> perhaps cancer.
- Coughing ang choking suggest “pharyngeal dysphagia” due to motor dysfunction –> Motor neuron disease causing bulbar or pseudobulbar palsy.
Odynophagia?
PAIN on shallowing.
Substernal sensation DURING shallowing –> Esophageal inflammation –> Candida, Herpes, CMV, peptic ulceration, caustic damage, esophageal perforation.
Remember ask about drugs.
GERD - typical features?
Site –> mid-line, retrosternal.
Radiation –> Throat, occasionally infra-scapular regions
Nature –> burning
Aggravating factors –> Worse after meals, when performing postures which raise the intra-abdominal pressure (bending, stooping, lying supine) + pregnancy.
Associated symptoms –> Acid/bitter taste (acid regurgitation), or sudden filling of the mouth with saliva (“waterbrash”).
Foods that worsen GERD?
Chocolate, alcohol, caffeine, fatty meals.
Drugs that worsen GERD?
CCBs
Anticholinergics
which act to lower the GOJ sphincter pressure.
Dyspepsia?
- Upper abdominal discomfort
- Bloating
- Belching
Dyspepsia - be alert for features suggestive of a serious pathology?
- Anemia
- Weight loss
- Dysphagia
- PR blood loss
- Melena
- Abdominal masses
Dysphagia - oral causes?
- Painful mouth ulceration
2. Oral/throat infections
Dysphagia - Neurological causes?
- Cerebrovascular event
- Bulbar and pseudobulbar palsies
- Myasthenia gravis
Dysphagia - Dysmotility?
- Achalasia
- Systemic sclerosis
- Presbyesophagus
Dysphagia - Mechanical causes?
- Pharyngeal pouch
- Esophageal cancer
- Peptic stricture
- Other benign strictures
- Extrinsic compression of the esophagus (large lung or thyroid tumor)
Vomiting - timing?
- Vomiting delayed >1h after meal –> Gastro-esophageal obstruction or gastroparesis.
- Early morning vomiting is typical of pregnancy or raised intracranial pressure.
Hematemesis - ask specifically?
- Amount of blood + exact nature.
- Previous bleeding episodes + treatment + outcome (previous surgery?).
- Smoking
- Drugs –> aspirin, NSAIDs, warfarin.
Remember –> Weight loss, dysphagia, abdominal pain and melena (consider cancer possibility)
Nature of vomitus - Bile?
Assess the presence/absence of bile.
Bile comes largely in 2 colors:
1. Green (biliverdin) often seen to color the vomitus in the absence of UNdigested food.
2. Yellow pigment (bilirubin) appears as orange, often occurring in small lumps.
Vomiting - acute etiology?
- GI infections
- Systemic bacterial infections
- Mechanical bowel obstruction
- Alcohol intoxication
- Acute upper GI bleed
- Urinary tract infection
Vomiting - chronic causes?
- Pregnancy
- Uremia
- Drugs
- Gastroparesis
Drugs that cause chronic vomiting?
- Narcotics
- Digitalis
- Aminophylline
- Cancer chemo
Vomiting - other causes?
- PUD
- Motor disorders (post-surgery or autonomic dysfunction).
- Hepatobiliary disease
- Alcoholism
- Cancer
Upper GI bleeding - etiology?
- Peptic ulceration
- Erosive or ulcerative esophagitis
- Gastritis
- Varices (esophageal/gastric)
- Gastric/esophageal tumors)
- Mallory-Weiss tear
- Dieulafoy’s lesion
- Vascular anomalies - angiodysplasia, AV malformation
- Hereditary hemorrhagic telangiectasia
- Connective tissue disorders
- Vasculitis
- Bleeding disorders
Nature of hematemesis?
- Large volume of fresh, red blood.
- Small streaks –> Minor trauma at the GEJ (Mallory-Weiss tear)
- Coffee-ground –> Blood that has been altered by exposure to stomach acid - appears brown and in small lumps.
Sites of abdominal pain and embryologic origin?
- Epigastric (foregut) –> Stomach, duodenum, liver, pancreas, gallbladder.
- Periumbilical (midgut) –> Small and large intestines including appendix.
- Suprapubic (hindgut) –> Rectum and urogenital organs.
Very localized abdominal pain?
May originate from the parietal peritoneum
Abdominal pain - radiation examples?
- Right scapula –> Gallbladder
- Shoulder-tip –> Diaphragmatic irritation
- Mid-back –> Pancreas
Abdominal pain - character?
- Colicky –> This is pain that comes and goes in waves and indicates obstruction of a hollow, muscled-walled organ (intestine, gallbladder, bile duct, ureter).
- Burning –> Usually indicates an acid cause and is related to the stomach, duodenum or lower end of esophagus.
Renal colic?
Colicky pain at the renal angles +/- loins, which are tender to touch, radiating to the groins/testicles/labia.
Typically –> Patient writhes around, unable to find a position that relieves the pain.
Bladder pain?
Diffuse severe pain in the suprapubic region.
Prostatic pain?
Dull ache which may be felt in the lower abdomen, rectum, perineum or anterior thighs.
Urethral pain?
Variable in presentation ranging from a “tickling” discomfort to a severe sharp pain felt at the end of the urethra (tip of the penis) and exacerbated by micturition.
Can be so severe that patients attempt to “hold on” to urine causing yet more problems!
Small bowel obstruction pain?
Colicky central pain associated with vomiting, abdominal distention +/- constipation.
Colonic pain?
As above under “small bowel” but sometimes temporarily relieved by defecation or passing flatus.
Bowel ischemia pain?
Dull, severe, constant, RUQ/Epigastric pain that can last hours and is often worse after eating fatty foods.
Pancreatic pain?
Epigastric, radiating to the back and partly relieved by sitting up + leaning forward.
Peptic ulcer pain?
Dull, burning pain in the epigastrium.
Typically episodic at night, waking the patient from sleep.
Exacerbated by eating and sometimes relieved by consuming milk or antacids.
Normal bowel habit?
Ranges from 3 times/day to once every 3 days.
Constipation is?
Passage of stool <3 times/week or stools that are hard or difficult to pass.
Thorough history of constipation should include?
- Duration
- Stool size and consistency
- Straining, particularly at the end
- Ass. symptoms - nausea/vomiting, weight loss
- Pain on defecation
- Rectal bleeding
- Intercurrent diarrhea
- Fluid and fibre intake
- Depression, lack of exercise
- Drugs
- Met. or endocrine diseases
- Neurological problems
Drugs associated with constipation?
- Codeine
- Antidepressants
- Aluminium
- Calcium antacids
Constipation - met. or endocrine causes?
- Thyroid disorders
- Hypercalcemia
- Diabetes
- Pheochromocytoma
- Hirschsprung disease
Constipation - neurological problems?
- Autonomic neuropathy
- Spinal cord injury
- MS
Diarrhea - definition?
Incr. in stool volume (>200mL daily) and frequency (3/day). Also a change in consistency to semi-formed or liquid stool.
Acute diarrhea is suggestive of?
Infection
Diarrhea - ask specifically?
- Color, consistency, offensive smell, ease of flushing.
- Duration
- Does the diarrhea disturb patient’s sleep?
- Is there any blood, mucus or pus?
- Associated pain or colic?
- Is there urgency?
- Nausea/vomiting, weight loss?
- Any difference if patient fasts? (osmotic vs secretory)
- Foreign travel
- Recent antibiotics
Constipation - etiology?
- Low-fibre diet
- Physical immobility
- Functional bowel disease
- Drugs (e.g. opiates, antidepressants, aluminium, antacids)
- Met. and endocrine diseases
- Neurological disorders
- Colonic stricture
- Anorectal disease
- Habitual neglect
- Depression
- Dementia
Diarrhea - etiology - malabsorption?
May cause steatorrhea - fatty, pale stool, EXTREMELY ODOROUS and difficult to flush.
Diarrhea - etiology - Incr. intestinal motility?
- Hyperthyroidism
2. Irritable bowel syndrome
Diarrhea - etiology - exudative?
Inflammation of the bowel causes small volume, frequent stools, often with blood or mucus (e.g. colonic carcinoma, Crohn, UC).
Diarrhea - etiology - osmotic?
Large volume of stool which disappears with fasting.
Causes: Lactose intolerance, gastric surgery.
Diarrhea - etiology - secretory?
High volume of stool which disappears with fasting. No pus, blood or excessive fat.
Causes: GI infections, carcinoid syndrome, villous adenoma of the colon, Z-E syndrome, VIPoma
Rectal bleeding - determine?
- Amount –> small amounts can appear dramatic, coloring toilet water red.
- Nature of the blood (red, brown, black)
- Is it mixed with stool or “on” the stool?
- Is it spattered over the pan, with the stool on only seen on the paper?
- Any associated features (mucus may indicate inflammatory bowel disease or colonic cancer).
Melena - bleed where?
Upper GI or right side of the colon.
Melena - what to ask about?
Do you take iron supplements/bismuth containing compounds?
Mucus - what is it?
Clear viscoid secretion of the mucus membranes.
Contains mucus, epithelial cells, leukocytes and various salts suspended in water.
Mucus - may indicate?
- IBD
- Solitary rectal ulcer
- Small or large bowel fistula
- Colonic villous adenoma
- Irritable bowel syndrome
Excessive flatus - feature of?
- Hiatus hernia
- Peptic ulceration
- Chronic gallbladder disease
- Air-shallowing (aerophagy)
- High-fibre diet
Causes of lower GI bleeding?
- Hemorrhoids
- Anal fissure
- Diverticular disease
- Colonic carcinoma
- Polyp
- Angiodysplasia
- IBD
- Ischemic colitis
- Meckel’s diverticulum
- Small bowel disease (tumor, diverticulae, intussusception, Crohn’s)
- Solitary rectal ulcer
- Hemobilia
Hemobilia?
Bleeding into the biliary tree.
Fat malabsorption?
- Pancreatic insufficiency - Chronic pancreatitis, CF.
- Celiac disease
- IBD
- Blind bowel loops
- Short bowel syndrome
Fat malabsorption - what does the patient tell?
- Pale stool
- Offensive smelling
- Poorly formed
- Difficult to flush (floats)
Jaundice - ask about?
- Color of the urine (dark in cholestatic jaundice).
- Color and consistency of the stools (pale in cholestatic jaundice)
- Abdominal pain (caused by gallstones).
Jaundice - ask especially about?
- Previous blood transfusions
- Past history of jaundice
- Drugs (e.g. antibiotics, NSAIDs, OCPs, phenothiazines)
- IV drug abuse
- Tattoos and body piercing
- Foreign travel
- Sexual history
- FHx of liver disease
- Alcohol consumption
- Personal contacts who also have jaundice
Jaundice - PREhepatic etiology?
- Hemolysis
- Gilbert
- Dubin-Johnson
- Rotor
- Hemodialysis
Jaundice - HEPATOCELLULAR etiology?
- Cirrhosis
- Acute hep - viral, alcoholic, autoimmune, drug-induced.
- Liver tumors
- Cholestasis from drugs - chlorpromazine.
Jaundice - Posthepatic etiology?
Obstruction of biliary outflow:
- Luminal –> Gallstones
- Wall pathology –> congenital bile abnormalities, PBC, trauma, tumor.
- External compression –> Pancreatitis, lymphadenopathy (!), pancr. tumor, Ampulla of Vater tumor.
5 causes of abdominal swelling - 5 F’s + 1:
Fat Fluid Flatus Feces Fetus \+ Tumor.
5 types of urinary incontinence?
- “True”
- Giggle
- Stress
- Urge
- Dribbling or overflow
True urinary incontinence?
Total lack of control of urinary excretion –> Suggestive of a fistula between the urinary tract and the exterior or a neurological condition.
Giggle urinary incontinence?
Incontinence during bouts of laughter - Common in young girls.
Stress urinary incontinence?
Leakage associated with a sudden Incr. in intra-abdominal pressure of any cause –> coughing, laughing, sneezing.
Urge urinary incontinence?
Intense urge to urinate such that the patient is unable to get to the toilet in time.
Causes of urge urinary incontinence?
- Over-activity of the detruser muscle
- Urinary infection
- Bladder stones
- Bladder cancer
Dribbling or overflow?
Continual loss of urine from a chronically distended bladder.
Typically in elderly males with prostate disease.
Terminal dribbling?
Male complaint - usually indicative of prostate disease.
Dysuria?
Pain on micturition –> described as “burning” or “stinging” and felt at the urethral meatus.
Ask whether it is throughout the passage of urine or only at the end (“terminal dysuria”).
Incomplete emptying suggests?
Detruser dysfunction or prostatic disease.
Intermittency?
Stop-start manner of urine flow.
Suggests –> BPH, bladder stones, ureteroceles
Oliguria - definition?
Scanty or low-volume urination and is defined as the excretion of <300mL urine in 24h.
Causes of oliguria?
Physiological –> Dehydration
Pathological –> Intrinsic renal disease, shock, or obstruction.
Polyuria should be differentiated from???
Urinary frequency - In polyuria we got LARGE volumes.
Causes of polyuria?
- Hysterical polydipsia
- DM
- Diabetes insipidus - failure of ADH
- Chronic renal failure –> defective urine concentration.
Polyuria - remember to ask?
Use of diuretics!
Weight loss in a patient with ascites?
BEWARE –> Ascites weighs 1kg/L and some patients with liver failure may have 10-20L of ascites - MASKING any “dry weight” loss.
Weight loss - try to determine?
- When the symptom first noticed.
- Quantify the problem - How and over what time period.
- Cause of anorexia - does eating make patient feel sick?
- Does eating cause pain? (ulcer, mesenteric angina, pancreatitis)
- Accompanying symptoms - Abdominal pain, nausea/vomiting, fever.
Weight loss - ALSO ask about?
- Color and consistency of stools (steatorrhea)
- Urinary symptoms
- Recent change in temperature tolerance
Combination of weight loss with incr. appetite may suggest?
May suggest malabsorption or thyrotoxicosis (or other hypermetabolic state).
The abdomen - PMH - Ask specifically?
- Previous surgeries –> including peri- and postoperative and anesthetic complications.
- Chronic bowel disease –> IBD
- Possible associated conditions –> diabetes with hemochromatosis.
The abdomen - DHx - Drugs that precipitate hepatitis?
- Halothane
- Phenytoin
- Chlorothiazides
- Pyrazinamide
- Isoniazid
- Methyl dopa
- Statins
- Sodium valproate
- Amiodarone
- Antibiotics
- NSAIDs
The abdomen - DHx - Drugs that precipitate cholestasis?
- Chlorpromazine
- Sulfonamides
- Sulfonylureas
- Rifampin
- Nitrofurantoin
- Anabolic steroids
- OCPs
The abdomen - DHx - Drugs that precipitate fatty liver?
- Tetracycline
- Sodium valproate
- Amiodarone
Drug that precipitate acute liver necrosis?
Paracetamol
The rest of history - Smoking?
- Incr. risk for peptic ulceration, esophageal cancer, colorectal cancer.
- Detrimental effect in Crohn
- Protect against UC
Rest of history - Family history?
Ask especially:
- IBD
- Celiac disease
- PUD
- Hereditary liver diseases (Wilson’s, hemochromatosis)
- Bowel cancer
- Jaundice
- Anemia
- Splenectomy
- Cholecystectomy
Rest of the history - SHx?
- Risk of exposure to hepatotoxins and hepatitis through occupation.
- Tattoos
- Illicit drug use (especially sharing needles)
- Social contacts with a similar phase (particularly relevant to jaundice)
- Recent foreign travel
Rest of history - Dietary history?
- Amount of fruit, vegetables and fibre in the diet.
- Evidence of lactose intolerance.
- Change in symptoms related to eating certain food groups
- Sensitivities to wheat, fat, caffeine, gluten.
The CAGE questionnaire?
C - Have you ever felt that you should Cut down your drinking?
A - Have you ever got Angry when someone suggested that you should cut down drinking?
G - Do you ever feel Guilty about your drinking?
E - Do you ever need an “Eye-opener” in the morning to steady your nerves or get rid of a hangover?
Framework for the abdominal examination?
- General inspection
- Hands
- Arms
- Axillae
- Face
- Chest
- Inspection of abdomen
- Palpation of abdomen - light/deep/specific organs/examination of hernial orifices/external genitalia.
- Percussion (+/- examination of ascites)
- Auscultation
- Digital exam of the anus/rectum/prostate
General inspection - Look especially for?
- High or low body mass
- State of hydration
- Fever
- Distress
- Pain
- Muscle wasting
- Peripheral edema
- Jaundice
- Anemia
Nails - examine for?
- Leukonychia
- Koilonychia
- Muerhrcke’s lines
- Clubbing
- Blue lunulae
Leukonychia?
Whitening of the nail bed due to hypoalbuminemia (eg malnutrition, malabsorption, hepatic disease, nephritic syndrome).
Koilonychia?
“Spooning” of the nails making a concave shape instead of the normal convexity.
Koilonychia - Causes?
Congenital/Chronic iron deficiency.
Muehrcke’s lines?
Transverse white lines –> Seen in hypoalbuminemic states including severe liver cirrhosis.
Clubbing - abdominal causes?
- Cirrhosis
- IBD
- Celiac disease
Blue lanulae?
Bluish discoloration of the normal lanulae seen in Wilson.
Palmar erythema?
“Liver palms”:
Blotchy reddening of the palms of the hands –> thenar/hypothenar.
Can also affect soles of feet.
Palmar erythema - associated with?
- Chronic liver disease
- Pregnancy
- Thyrotoxicosis
- RA
- Polycythemia
- Chronic leukemia (rarely)
It can also be a normal finding.
Dupuytren contracture?
- Thickening and fibrous contraction of the palmar fascia.
- Early –> Palpable irregular thickening of the fascia is seen - especially overlying the 4th and 5th metacarpals.
- Often BILATERAL - May also affect the feet.
Dupuytren contracture - causes?
Seen especially in alcoholic liver disease but may also be seen in manual workers (or may be familial).
Hepatic flap - associated with?
Hepatic encephalopathy - precipitated by:
- Infection
- Diuretic medication
- Electrolyte imbalance
- Diarrhea
- Constipation
- Vomiting
- Centrally acting drugs
- Upper GI bleeding
- Abdominal paracentesis
- Surgery
Examine the upper limb for any signs of?
- Bruising
- Petechiae
- Muscle wasting
- Scratch marks (excoriations)
Bruising may be a sing of?
- Hepatocellular damage –> coagulation disorder.
- Thrombocytopenia –> hypersplenism.
- Marrow suppression with alcohol.
Petechia may be a sign of?
Pin-prick bleeds which do not blanche with pressure –> Sign of THROMBOCYTOPENIA.
Upper limb - be careful not to miss?
- AV fistulae
2. Hemodialysis catheters
Axillae - examine for?
- Lymphadenopathy
2. Acanthosis nigricans
Acanthosis nigricans?
Thickened, blackening of the skin. Velvety in appearance –> May be associated with INTRA-ABDOMINAL malignancy.
Eyes - look especially for?
- Jaundice
- Anemia
- Kayser-Fleischer rings
- Xanthelasma
Kayser-Fleischer rings?
Greenish-yellow pigmented ring just inside the cornea-scleral margin - due to Cu deposition.
Mouth - look for?
- Angular stomatitis
- Circumoral pigmentation
- Dentition
- Telangiectasia
- Gums
- Breath
- Tongue
- Candidiasis
Angular stomatitis - sign of?
Reddening and inflammation at the corners of the mouth --> A sign of: 1. Thiamine 2. B12 3. Iron deficiencies :).
Circumoral pigmentation - seen in?
Hyperpigmented areas around the mouth - Peutz-Jegher’s syndrome.
Dentition?
Note false teeth or if there is evidence of tooth decay.
Telangiectasia - seen in?
Osler-Weber-Rendu syndrome.
Gums - look for?
- Ulcers –> Celiac disease/IBD/Behcet/Reiter.
2. Hypertrophy –> Pregnancy/Phenytoin/Leukemia/Scurvy/Gingivitis
Breath - especially for?
- Fetor hepaticus - sweet-smelling breath.
- Ketosis - sickly sweet pear-drop smelling breath.
- Uremia - a fishy smell.
Tongue - look especially for?
- Glossitis
- Macroglossia
- Leukoplakia
- Geographical tongue