Deja - Internal - Pulmonology Flashcards
What is a common underlying cause of decr. RR?
Drugs - Opiates.
What is a common underlying cause of incr. RR?
- Infection
2. Trauma
When is low FiO2 mostly a problem?
High altitudes or closed spaces with no fresh air or fire.
Give an example of hypoxia caused by underutilization.
When there is impairment of cytochrome due to toxins/poisons, such as cyanide.
What are some examples of causes of V/Q mismatch?
- Pulm. embolism.
- Underlying lung disease (lung cancer or COPD).
- Bronchospasm.
- Pneumonia.
- Pulm. edema.
What is the clinical sign of CO poisoning?
Cherry red lips and nails.
PaCO2 and A-a gradient - Hypoventilation:
PaCO2 –> UP.
A-a gradient –> N.
PaCO2 and A-a gradient - R-L shunt:
PaCO2 –> UP.
A-a gradient –> UP.
PaCO2 and A-a gradient - Low FiO2:
PaCO2 –> N.
A-a gradient –> N.
PaCO2 and A-a gradient - V/Q mismatch:
PaCO2 –> N.
A-a gradient –> UP.
What type of hypoxemia does not improve with incr. FiO2?
R–>L shunt.
What is the male:female of emphysema?
10:1.
What are the pathognomonic symptoms associated with emphysema?
- Pursed lip breathing (with prolonged expiratory phase).
- Barrel chest.
- Hyperventilation.
- Weight loss.
ABGs in a person with early-stage emphysema?
Low PaCO2.
N/Low PaO2.
What is the difference in symptomatology in chronic bronchitis vs emphysema?
Chronic bronchitis includes a persistent productive cough as well as more hypoxia than seen in emphysema, and patients are usually overweight.
What do you expect to see in an ABG in a person with chronic bronchitis?
High PaCO2.
Low PaO2.
Compensated respiratory acidosis.
What are the only treatments proven to extend life in COPD?
O2 therapy + smoking cessation.
What are the MC pathogens that colonize the lung in an individual with bronchiectasis?
SHiPS
S.aureus. H.flu i Pseudomonas S.pneumoniae
How do you treat the organism that most commonly infect the lung in bronchiectasis?
3rd gen cephalosporins.
How can bronchiectasis be diagnosed?
High res CT –> Shows TRAM TRACK lung markings.
What is often the 1st symptom of asthma that a patient will often describe?
Nighttime cough - for some people this is the only symptom.
ABGs in an asthma attack?
Hypoxia and respiratory alkalosis.
What is a sign of impending respiratory failure in a case of asthma?
ABG that shows normalizing PaCO2.
What is the classic diagnosis that you should think of if the CBC of an asthmatic demonstrates eosinophilia?
Churg-Strauss syndrome.
What is the 1st line treatment for an acute asthma exacerbation?
- O2.
- Bronchodilators (includes beta-agonist and ipratropium).
- Steroids.
What is a 2nd line treatment for an acute asthma attack?
Subcutaneous epinephrine + MgSO4.
Asthma classification by symptoms:
- Mild intermittent –> >2/wk + nighttime >2/month.
- Moderate persistent –> Daily asthma with nighttime >1/wk.
- Severe persistent –> Continuous symptoms.
What is the MCC of atelectasis?
A postoperative patient who is non ambulatory for a long period of time.
What types of chemotherapy can cause a restrictive lung disease?
- Busulfan
2. Bleomycin
What lab tests should be sent in order to evaluate the pleural fluid?
- Fluid + SERUM protein, glucose, LDH.
- Fluid culture + gram stain.
- Fluid cytology.
- Cell count with DIFFERENTIAL.
- Additionally:
a. Amylase.
b. AFB.
c. ANA.
d. RF.
e. pH.
What defines an exudative effusion?
If ANY of the following is true, the fluid effusion is considered exudative:
Pleural protein/Serum protein > 1/2.
Pleural LDH/Serum LDH >0.6.
Pleural LDH>200.
What can low glucose (glucose <60) in the pleural fluid be associated with?
- Tumor.
- Empyema.
- Rheumatologic etiology.
- Parapneumonic exudate.