oesophageal disorders Flashcards
How is food moved through oesophagus
Oesophageal peristalsis produced by the circular muscles
What innervates the oesophageal peristalsis and relaxation of the lower oesophageal sphincter (LOS)
Vagus nerve
Describe how heartburn might feel
Retrosternal heartburn or discomfort
What causes heartburn
acid reflux
What does persistent reflux and heartburn lead to
Gastro-oesophageal reflux disease (GORD)
What is dysphagia
Difficulty swallowing foods
What can cause dysphagia
Benign stricture
Malignant stricture - oesophageal cancer
Motility disorder (achalasia)
Stricture is most common cause
How is oesophageal disease investigated
Endoscopy when patient has ALARM features
Describe hypermotility of oesophagus
Diffuse oesophageal spasm - corkscrew appearance on Ba swallow
Severe episodic chest pain with or without dysphagia
What is the treatment for hyper-motility of oesophagus
Smooth muscle relaxants
What is achalasia
Functional loss of the myenteric plexus ganglion in the distal oesophagus and lower oesophageal sphincter
Failure of LOS to relax which causes distal obstruction of oesophagus
What is the presentation of achalasia
Progressive dysphagia for solids and liquids
Weight loss
Chest pain - sometimes
Regurgitation and chest infection
What is the treatment of achalasia
Nitrates, calcium channel blockers
Botulinum toxin pneumatic balloon dilation
Surgical - myotomy
What does achalasia increase the risk of
Squamos cell oesophageal carcinoma
What are the symptoms of GORD
Heart burn
Cough
Water brash
Sleep disturbance