alcohol related liver disease Flashcards
What breakdown product of alcohol is toxic
Acetaldehyde
How does spontaneous bacterial peritonitis present
Abdo pain
Fevors
Rigors
Renal impairment
Signs of sepsis
How does liver disease cause spontaneous bacterial peritonitis
End stage liver disease can result in ascites which can then get infected
What is the treatment of spontaneous bacterial peritonitis
IV antibiotics - cefotaxime or ceftriaxone
Ascitic fluid drainage
IV albumin infusion - increases vascular volume which reduces recurrence of ascites and improves renal fluid
How does alcoholic hepatitis present
Jaundice
Encephalopathy
Loss of liver function if decompensation occurs
How is alcoholic hepatitis diagnosed
Raised bilirubin
Raissed GGT and ALP
alcoholic history
What reduces alcohol withdrawal symptoms
Benzodiazepine
When are oral steroids given to alcoholic hepatitis
Maddreys discriminent function >32
Why is thiamine (Vit B) essential in treatment for alcoholic hepatitis
They are usually deficient in it (Vit B) and it can cause brain damage and korsakoffs encephalopathy
What does AAT>ALT mean
Alcoholic liver disease
What is the treatment of steatohepatitis
fatty liver disease - weight loss and exercise
