Oesophageal Carcinoma Flashcards by Liam Lennox | Brainscape

Q

Histology

A

Adenocarcinoma (80%)
Squamos cell carcinoma

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Q

AETIOLOGY

Risk factors

A

Male
Low socioeconomic status
Adenocarcinoma
- GORD and Barrett’s
- Hiatus hernia
Squamous cell carcinoma
- Smoking
- Alcohol
- FH
- High temperature drinks and food

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Q

CLINICAL FEATURES

Presentation

A

Dysphagia
Odynophagia (pain on swollowing)
Weight loss

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Q

INVESTIGATIONS

First choice

A

Oesophagogastroduodenoscopy (OGD) with biopsy
Comprehensive metabolic profile - advanced cases show hypokalaemia, increase creatinine and serum urea/nitrogen
CT for staging

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Q

MANAGEMENT

General principles

A

If low grade endoscopic resection with or without ablation
If higher grade and surgical candidate oesophagectomy
If higher grade and not surgical candidate chemotherapy and radiotherapy alone

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