ocular: parasym (muscarinic shit)

Question 0

what are the muscarinic agonists used to tx?

Answer 0

cataract surgery, glaucoma tx.

Question 1

3 direct muscarinic agonists and what do they do to the eye?

Answer 1

1. acetylcholine
2. pilocarpine HCl
3. carbachol

muscarinic agonists –> pupillary constriction, inc aque outflow

Question 2

ADRs of muscarinic agonists and the indirect muscarinic agonist?

Answer 2

bronchospasms, salivation, lacrimation, sweating, n/v/d/abd pain/tenesmus

Question 3

indirect muscarinic agonist used to produce cycloplegia for eye exams and improve discomfort during eye inflm (ueveitis)?

Answer 3

echothiophate iodide

Question 4

irreversibly binds cholinesterase? (Acid, pills, carbs –> hallucinations (echoes))

Answer 4

echothiophate

Question 5

what are the antimuscarinics and what’s the MOA? (at scotts, homer cycles tropicals)

Answer 5

1. atropine
2. scopolamine
3. homatropine
4. cyclopentolate
5. tropicamide

pupillary dilation and paralysis of ciliary body

Question 6

for eye exams to produce cycloplegia, and also relieve discomfort assoc with ueveitis

Answer 6

echothiophate, atropine, scopolamine, homatropine, cyclopentolate, tropicamide

Question 7

ADRs assoc with antimuscarinics?

Answer 7

ataxia, nystagmus, restlessness, mental confusion, hallucinations, violent and aggressive behavior, insomnia, photophobia, urinary retention