Obstructive Therapeutics

Question 1

what is the management for intermittent asthma?

Answer 1

SABA

Question 2

what is the management for mild, persistent asthma?

Answer 2

1. SABA

2. ICS

Question 3

what is the management for moderate/severe asthma?

Answer 3

1. SABA
2. ICS
3. • LABA/LAMA or theophylline
4. oral steroid

Question 4

name an inhaled steroid

Answer 4

beclomethasone

Question 5

how should ICS be given in COPD?

Answer 5

as an ICS/LABA/LAMA

Question 6

name a cromone

Answer 6

cromoglycate

Question 7

what is the MoA of cromoglycate?

Answer 7

mast cell stabiliser

Question 8

what disease is cromoglycate used for?

Answer 8

asthma

Question 9

name a leukotriene receptor antagonist

Answer 9

montelukast

Question 10

name an anti-IgE monoclonal antibody for asthma

Answer 10

omalizumab

Question 11

how do beta agonists work?

Answer 11

stimulate bronchial smooth muscle beta 2 recpetors

Question 12

name a SABA

Answer 12

salbutamol

Question 13

name a bi daily LABA

Answer 13

salmeterol

formoterol

Question 14

name some once daily LABAs

Answer 14

indacaterol
vilanterol
oldaterol

Question 15

how do muscarinic antagonists work?

Answer 15

block post junctional end plate M3 receptors

Question 16

name a SAMA

Answer 16

ipratropium

Question 17

name a LAMA

Answer 17

tiotropium

Question 18

what muscarinic antagonost can be used in asthma?

Answer 18

tiotropium

Question 19

what methylxanthine can be given orally for maintenance therapy?

Answer 19

theophylline

Question 20

what methylxanthine can be given for acute attacks?

Answer 20

IV aminophylline