Asthma Flashcards
what is asthma?
recurrent and reversible obstruction of the airways in response to a stimuli
name some possible triggers for an asthma attack
allergens exercise infections smoke dust
what does chronic asthma involve?
pathological changes in the bronchioles due to long standing inflammation
what is involved in the immediate phase of an asthma attack?
bronchospasm
what is involved in the delayed phase of an asthma attack?
inflammatory reactions
what three drugs can be used as relievers in asthma?
SABAs
LABAs
CysLT antagonists
what drugs can be used as controllers and preventers in asthma?
glucocorticoids
cromoglicate
monoclonal IgE antibodies
methyxanthines
what are the three types of beta two adrenoceptor agonists that can be used in asthma?
SABA - short acting
LABA - long acting
ultra LABA
name two SABAs
salbutamol
terbutaline
what is the first line treatment for mild, intermittent asthma
SABAs
when are SABAs given?
when needed
name some possible adverse effects of SABAs
tachycardia
fine tremor
arrythmia
hypokalaemia
name two LABAs
salmeterol
formoterol
what drug can be useful for nocturnal asthma and why?
LABAs
act for around 8 hours
when are LABAs given?
as add on therapy for inadequately controlled asthma
co-administered with a glucocorticoid
