Obstetricia Flashcards

1
Q

M. A. de Oxitocina

A

Unión a receptor OXTR
-> Prot. Gq -> Aumento de
Ca2+ -> Activa MLCK ->
Contracción del músc.
liso uterino (efecto
“uterotónico”

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2
Q

Usos de oxitocina

A

Inducción y
mantenimiento del
parto (1ª línea)
Prevención y Tx de
hemorragia post-
parto (1ª línea)

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3
Q

Oxitocina

A
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4
Q
A
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5
Q

M. A. de Misoprostol

A

Unión a receptor EP3
-> Prot. Gq -> Aumento de
Ca2+ -> Activa MLCK ->
Contracción del músc.
liso uterino (efecto
“uterotónico”)

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6
Q

Usos de Misoprolol

A

Prevención y Tx de
hemorragia post-parto
Tx de de aborto
incompleto
Otras: prevención de
úlceras GI por AINEs

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7
Q
A
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8
Q
A
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9
Q
A
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10
Q

M. A. de Ergometrina
(ergonovina)

A

Agonista de 5-HT (2B) y
alfa 1 adrenérgico -> Prot.
Gq -> Aumenta Ca2+ -> Vasoconstricción

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11
Q

Usos de Ergometrina (ergonovina)

A

Prevención y Tx de
hemorragia post-parto (efecto
uterotónico)

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12
Q

Usos de Atosibán

A

Tocolíticos de 1ª línea:
Efecto hasta por 2-7 días

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13
Q
A
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14
Q
A
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15
Q

M. A. de Nifedipino

A

Antagonista de
canales de Ca2+ tipo
L (vasoselectivo)
-> Efecto tocolítico

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16
Q

Usos de Nifedipino

A

Tocolíticos de 1ª línea:
Efecto hasta por 2-7 días
*Nifedipino: Tx de HAS (2ª
línea) y angina estable

19
Q

M. A. de Indometacina

A

Inhibidor de la
ciclooxigenasa (COX
1 y 2) -> Impide
formación de la
PGE2 (que mantiene
ductus arterioso
permeable y es
uterotónica)