Obs and gynae

Question 1

When is the triple test done? And what is it?

Answer 1

Done at 16 weeks

• afp
• beta HCG
• unconjugated estriol

Question 2

First trimester Downs screening

Answer 2

• nuchal thickness
• papp-a
• HCG

Question 3

Second trimester Down’s screening?

Answer 3

• HCG

- afp

Question 4

What does HCG do in pregnancy?

Answer 4

Prevents involution of corpus luteum

-effect on testes (male fetus development)

Question 5

What does human chorionic somatomammotropin do?

Answer 5

Produced from week 5 of pregnancy
Growth hormone like effect - protein and tissue formation
Causes a decrease in insulin sensitivity in mother = more glucose for baby
Involved in breast development

Question 6

Indicator of fetus viability

Answer 6

Estriol level

Question 7

What are sertoli cells

Answer 7

Sertoli cells are the somatic cells of the testis that are essential for testis formation and spermatogenesis

Question 8

Leydig cells

Answer 8

LH causes the leydig cells to produce testosterone

Question 9

GFR and pregnancy

Answer 9

Decreases when sitting
Increases when supine
Big increase when in lateral position and sleeping

Question 10

What causes insulin resistance during pregnancy?

Answer 10

Human chorionic somatomammotropinn
Cortisol
Growth hormone

Question 11

Oestrogen/progesterone and uterine contractility

Answer 11

Oestrogen increases contractility

Progesterone decreases contractility

Question 12

Where is oxytocin released from?

Answer 12

The posterior pituitary

Question 13

When can you make a diagnosis of gestational diabetes?

Answer 13

Diagnosis made at 28 weeks

Question 14

How do diagnose congenital adrenal hyperplasia?

Answer 14

elevated 17-hydroxyprogesterone

Question 15

Most common deficiency in congenital adrenal hyperplasia

Answer 15

21-hydroxylase deficiency

Question 16

Hirsutism developing before puberty is suggestive of what?

Answer 16

Congenital adrenal hyperplasia

Question 17

Treatment of neuroleptic malignant syndrome

Answer 17

Bromocriptine

Question 18

What does LH do?

Answer 18

stimulates androgen secretion from the ovarian theca cells

Question 19

Treatment of puerperal pyrexia?

Answer 19

Clindamyin and gentamicin

Question 20

Causes of polyhydramnios?

Answer 20

Duodenal atresia, anencephaly

Question 21

Treatment of hyperemesis gravidarum?

Answer 21

Promethazine or cycizine

Question 22

When is the bump palpable at the xiphoid sternum?

Answer 22

36 weeks

Question 23

When is the bump palpable at the umbilicus?

Answer 23

20 weeks

Question 24

Treatment of gonorrhoea?

Answer 24

IM ceftriazone and azthromycin

Question 25

This type of tumour is associated with Peutz Jegher?

Answer 25

Sertoli-leydig tumour

Question 26

“Coffee bean nuclei”

Answer 26

Brenner tumour