heme 2 Flashcards
What might cause a prolonged APTT?
Haemophilia
Heparin therapy
Treatment for von willebrands disease?
Tranexamic acid, desmopressin, factor VIII concentrate
Side effects of heparin?
Bleeding
Heparin induced thrombocytopenia
Osteoporosis
Symptoms of myeloma
Anaemia, bone pain, infections, renal failure, hypercalcaemia
What type of ig in waldenstroms?
IgM
Most common type of non-hodgkins?
Diffuse large B cell
What type of haemolysis occurs in G6PD?
Intravascular haemolysis
What type of haemolysis occurs in hereditary spherocytosis?
Extravascular haemolysis
What can myelodysplasia transform into?
Can transform into AML
The most common inherited thrombophilia
Factor V Leiden
Why does factor V leiden increase your risk of clots?
Factor V is inactivated much more slowly by protein C
t(8:14)
Burkitt’s lymphoma
Most common type of non-hodgkins lymphoma
Follicular
What is Felty’s syndrome?
Rheumatoid arthritis with hypersplenism and neutropenia
Threshold for platelet transfusion
Need to transfuse when platelets <30