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OBGYN > OBN: Fetal Development > Flashcards

OBN: Fetal Development Flashcards

1
Q

[Lung development]

pseudoglandular stage; growth of intrasegmental bronchial tree

A

5-17 weeks

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2
Q

[Lung development]

chest wall movements detected sonographically

A

11weeks

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3
Q

[Lung development]

canalicular stage; 2nd bronchial cartilage plates extend peripherally

A

16-25w

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4
Q

[Lung development]

canalicular lung development nearly complete

Type II pneumocytes secrete surfactant

A

24 weeks

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5
Q

[Lung development]

terminal sac stage; presence of primitive pulmonary alveoli

A

> 25 weeks

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6
Q

[Amniotic fluid source]

Early pregnancy

A

Maternal plasma as ultrafiltrate

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7
Q

[Amniotic fluid source]

2nd trimester

A

ECF diffused through fetal skin

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8
Q

[Amniotic fluid source]

12 weeks

A

fetal kidney

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9
Q

[Fetotoxic agents]

Renal damage, hypocalvaria

all trimester

A

ACEi

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10
Q

[Fetotoxic agents]

multiple gross anomalies

first trimester

A

Aminopterin

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11
Q

[Fetotoxic agents]

musculinization of female fetus

second and third trimester

A

androgens

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12
Q

[Fetotoxic agents]

neural tube defects

first trimester

A

Carbamazepine

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13
Q

[Fetotoxic agents]

promonged symptomatic neonatal hypoglycemia

all trimesters

A

Chlorpropamide

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14
Q

[Fetotoxic agents]

clear cell vaginal adenoCA; vaginal adenosis

all trimesters

A

Diethystilbestrol

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15
Q

[Fetotoxic agents]

ebstein anomaly

First, third trimester

A

Lithium

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16
Q

[Fetotoxic agents]

mobius sequence

First trimester

A

Misoprostol

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17
Q

[Fetotoxic agents]

major malformation of the face, limbs, other organs

first trimester

A

Mycophenolate mofetil

18
Q

[Fetotoxic agents]

cutis laxa

first trimester

A

peniclillamine

19
Q

[Fetotoxic agents]

poor suck reflex and feeding

all trimesters

A

phencylidine

20
Q

[Fetotoxic agents]

Fetal hydantoin syndrome

all trimesters

A

phenytoin

21
Q

[Fetotoxic agents]

congenital goiter

all trimesters

A

PTU

22
Q

[Fetotoxic agents]

Discoloration and defects of teeth and altered bone growth

A

Tetracycline

23
Q

[Fetotoxic agents]

phocomelia

first trimester

A

Thalidomide

24
Q

[Fetotoxic agents]

hypoplastic nasal bridge
chondrodysplasia

first trimester

A

warfarin

25
Q

[Fetotoxic agents]

hypoplastic left heart syndrome, micropthalmia/anopthalmia, clefts, ASD

A

Nitrofurantoin

26
Q

[Fetotoxic agents]

gray baby syndrome

A

chloramphenicol

27
Q

[Fetotoxic agents]

nephrotoxicity and ototoxicity in preterm infants

A

Gentamicin

Streptomycin

28
Q

[Fetotoxic agents]

clover leaf skill, wide nasal bridge, low set ears, micrognathia, limb abnormalities

A

methotrexate

29
Q

[Fetotoxic agents]

irreversible hypothyroidism

risk of thyroid CA

A

Radioiodine

30
Q

[Fetotoxic agents]

fetal growth and behavioral abnormalities

A

Lead

31
Q

[Fetotoxic agents]

disturbances in neuronal cell division and migration; avoid eating shark, swordfish, king mackerel tilefish, albacore tuna

A

mercury

32
Q

[Fetotoxic agents]

most potent teratogen

A

retinoids

33
Q

____ mIU/day of retinol causes defects

A

> 10,000 mIU/day

34
Q

[Fetotoxic agents]

SSRI that can cause ASD and VSD

A

Paroxetine

35
Q

[Genetic Abnormality]

most common non-lethal trisomy

A

Down Syndrome

Trisomy 21

36
Q

[Genetic Abnormality]

strawberry shaped cranium

A

Edwards Syndrome

Trisomy 18

37
Q

[Genetic Abnormality]

holoprosencephaly

A

Patau Syndrome

Trisomy 13

38
Q

[Genetic Abnormality]

only monosomy compatible with life

A

Turner

45, XO

39
Q

[Genetic Abnormality]

most common sex chromosome abnormality

A

Klinefelter Syndrome

47, XXY

40
Q

[Genetic Abnormality]

microdeletion
abnormal laryngeal development “Cat like” cry

A

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OBGYN (33 decks)

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