GYN: Abnormal Uterine Bleeding Flashcards
Cut-of frequency, regularity, duration, and volume of normal menstruation
Frequency: every 24-38 days
Regularity: (+/-) 2 to 20 days
Lasting 4.5 to 8 days
Volume: 5 to 80mL
Chronic AUB is defined as ____ month wherein majority of the symptoms are present
6 months
____ are risk factor for AUB-Polyp
- Tamoxifen use
- Infertility
- HRT (estrogen-only and combined)
Hypothesis of the development of AUB-A
- Increase in endometrial surface
- Altered PGE/PGF2a balance
- Hampered myometrial contractility
- Abnormal myometrial angiogenesis associated with fragile
Pathophysiology og AUB-L
- Increased surface area of the endometrium due to mechanical distortion
- Ulceration and hemorrhage of endometrium overlying the submucous fibroids
- Interference by the myomas with the normal uterine hemostasis
- Mechanical compression of the venous drainage by the myomas at any site
- Dilatation of the venous plexus draining the endometrium
What is the FIGo classification of a myoma where it contacts the endometrium and 100% intramural
FIGO 3
FIGO 4 - intramural
FIGO 5 - subserosal >= 50%, intra mural
FIGO 6 - subserosal < 50% untramural
What is the normal menstrual cycle length?
28 +/- 7 days
What is the normal duration of flow in each menstrual cycle?
4 days
but can go up to 7 days
What is the normal menstrual blood flow loss
35mL average
55 to 60mL
What is the average iron loss per menses?
16mg
What are the components of endometrial polyp
- Endometrial gland
2 Endometrial stroma - Central vascular channels
What are the possible causes of endometrial polyp?
Estrogen stimulation
[AUB-L]
<50% intramural
SM 1
[AUB-L]
> / 50% intramural
SM2
[AUB-L]
contacts endometrium, 100% intramural
O3
