obf 1 Flashcards

1
Q

also know as joint fluid

a. synovial fluid
b. serous fluid
c. amniotic fluid

A

synovial fluid

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2
Q

this fluid formed as a non selective ultrafiltrate of plasma

a. synovial fluid
b. serous fluid
c. amniotic fluid

A

synovial fluid
- formed as a non selective ultrafiltrate of plasma across the synovial membrane except for the exclusion of high molecular weight

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3
Q

responsible for the viscosity of synovial fluid

a. albumin
b. proteins
c. hyaluronic acid

A

hyaluronic acid

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4
Q

functions of synovial fluid, except:

a. to provide lubrication between 2 membranes as the surface move to each other
b. lubricates the joint
c. reduce the friction between bones
d. provides nutrients to the articular cartilage

A

FUNCTIONS OF SYNOVIAL FLUID

  1. LUBRICATES THE JOINT
  2. REDUCE THE FRICTION BETWEEN BONES
  3. PROVIDES NUTURIENTS TO THE ARTICULAR CARTILAGE
  4. LESSEN THE SHOCK OF JOINTY COMPRESSION OCCURING DURING ACTIVITIES

ANS: A

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5
Q

in synovial fluid, if possible the patient should be on fasting for how many hours

a. 8-12 hours
b. 6-8 hours
c. 4-6 hours

A

if possible the patient should be on fasting for 4 to 6 hours to allow for the equilibration of chemical constituents between plasma and synovial fluid

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6
Q

order of distribution
in what order of tube to send in hematology

a. 1st
b. 2nd
c. 3rd
d. 4th

A

collection tube disorder on SYNOVIAL FLUID

1st - chemistry and serology

2nd - hematology and cytology

3rd - microbiology

CHeM

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7
Q

what kind of edta to be used in hematology on synovial fluid

a. liquid form
b. dry form

A

liquid form

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8
Q

synovial fluid : volume for inflammation

a. 0.1 to 3.5 ml
b. >15 ml
c. >25ml

A

normal: 0.1 to 3.5 ml
inflammation: >25ml

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9
Q

test for the viscosity of synovial fluid

a. toluidine blue
b. ropes / mucin clot test
c. catalase

A

rope or mucin clot test ( hyaluronate polymerization test)

reagent: 2- 5 % of acetic acid

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10
Q

friable clot what grading it is in rope/ mucin clot

a. good
b. fair
c. low

A

low

good - solid clot
fair - soft
low - friable clot
poor - no clot

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11
Q

normal color of synovial fluid

a. colorless to pale yellow
b. deeper yellow
c. greenish inge
d. milky

A

colorless to pale yellow - normal

turbid - wbc, synovial cell debris, fibrin
deeper yellow - inflammation
greenish tinge - bacterial infection
red - traumatic tap , hemorrhagic arthritis
milky - crystals

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12
Q

promotes clot in synovial fluid

a. hyaluronic acid
b. acetic acid
c. toluidine blue

A

acetic acid

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13
Q

most predominant wbc cells can be found on a normal synovial fluid

a. monocyte
b. neutrophil
c. lymphocyte
d. macrophages

A

monocytes and macrophages - 65%
neutrophil - 25%
lymphocytes - 15%

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14
Q

similar to macrophage, but may be multinucleated resembling a mesothelial cell

a. LE cells
b. synovial lining cell
c. RA cell
d. reiter cell

A

synovial lining cell

description : similar to macrophage, but may be multinucleated resembling a mesothelial cell

significance : normal

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15
Q

neutrophil containig characteristics ingested
“ ROUND HOMOGENOUS BODY “

a. LE cells
b. synovial lining cell
c. RA cell
d. reiter cell

A

LE cell

round homogenous body

significance : lupus eryrhematous

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16
Q

vacuolated macrophage with ingested neutrophil

a. LE cells
b. synovial lining cell
c. RA cell
d. reiter cell

A

reiter cell

17
Q

neutrophil with dark cytoplasmic granules containing immune complexes

a. LE cells
b. synovial lining cell
c. RA cell
d. reiter cell

A

RA cell (ragocyte)

18
Q

cells/ inclusion that can be seen in TUBERCULOSIS, SEPTIC AND RHEUMATOID ARTHRITIS

a. rice bodies
b. fat droplets
c. ochronotic shards
d. hemosiderin

A

cells / inclusions : rice bodies

description : macros - polished rice
micros - shows collagen and fibrin
they are fragments of degenerating proliferative synovial cells or microinfarcted synovium

19
Q

cells or inclusions that can be seen as ground pepper appearance

a. rice bodies
b. fat droplets
c. ochronotic shards
d. hemosiderin

A

onchronotic shards

significance : joint prosthetis , onchrosis

20
Q

what is the difference between blood glucose and synovial glucose

a. more than 20%
b. less than 20%
c. less than 10%
d. more than 10%

A

it should be LESS THAN 10%

21
Q

what chemistry test should be test for monitoring the severity and prognosis of rheumatoid arthritis

a. glucose
b. lactate
c. acp
d. protein

A

lactate and acp

22
Q

normal value : <250mg/dl
increased : infection

a. glucose
b. lactate
c. acp
d. protein

A

lactate

23
Q

what chemistry test to be don in synovial fluid with the results is increase in inflammatory and hemorrhagic disorders

a. glucose
b. lactate
c. protein’
d. uric acid

A

protein

n.v : <3 g/dl