Obesity Flashcards
What BMI is classed as overweight?
What is classed as obese?
> 25
> 35
What endocrine conditions may cause obesity?
Hypothyroidism
Cushing’s
Health risk of obesity:
- CVD
- Metabolic syndrome
- Cancer
- Respiratory
- Gallbladder
- Bones
HTN
High cholesterol
IHD
Stroke
T2DM, NAFLD
Breast
Colorectal
Endometrial
Cholangiocarcinoma
Obstructive sleep apnoea
Obesity hypoventilation syndrome
Gallstones
Osteoarthritis
Management:
First-line
Second-line
Third-line
Fourth-line
Weight-loss diet - sustained weight loss
Regular exercise >150/wk
Orlistat - OTC medication used to help people lose weight.
Bariatric surgery
Orlistat:
MOA
Indications
Obvious side effects if you no MOA
Lipase inhibitor so reduces GI absorption of fat, therefore, reducing weight
BMI >30 and failure of the behavioural approach
Steattorhoea and anal leakage
Flatulence
Abdominal distention and pain
Faecal urgency/incontinence