ALF - Other Causes***** Flashcards
Non-paracetamol drug induced ALF is a diagnosis of exclusion.
What hep virus is commonly misdiagnosed as a drug induced liver failure?
What drug used to treat TB? - R
What antibiotic used to Rx UTI’s could be cause?
What anti-epileptic drugs could be a cause?
Why are NSAID’s avoided?
Hep E
Rifampicin
Nitrofurantoin
Due to the increased hepatorenal syndrome
Valproate
Ischaemic injury:
What 2 recreational drugs can cause this?
Cocaine
MDMA
Viral hepatitis:
What 3 hep viruses are you concerned about?
Autoimmune hepatitis - what is needed for diagnosis?
Hep A, B and E
Autoantibodies and immunoglobulin testing
What is it called if you can’t find a reason for the ALF?
Indeterminante ALF
List some pregnancy related liver disease?
HG
Pre-eclampsia and eclampsia (due to hepatic rupture)
HELLP syndrome
Acute fatty liver of pregnancy
Miscellaneous cause of ALF:
Malignant infiltration of the liver can present as ALF.
What toxins can cause ALF? - 4
Budd-Chiari syndrome - what is it?
Wilson’s disease can also cause it. What is it?
Cocaine
Ecstasy - MDMA
Herbal remedies
Mushrooms
ALF with previous hepatic vein thrombosis
Inability for the liver to metabolise copper properly so there is a build up copper