Obesity Flashcards
What does the release of leptin do?
Increases appetite.
What are adipokines?
Proteins secreted by adipocytes
What are examples of adipokines?
Leptin CRP TNF a IL6 Oestrogen
What are foam cells and what is their significance?
Foam cells form when macrophages accumulate fat.
Found in atherosclerotic plaques
Which part of the adipose cell is under stress in obesity?
ER
How does orlistat work?
Inhibits lipase from breaking down fat which can be absorbed in the intestine. Instead fat is excreted.
What are the three types of gastric reducing surgery?
Gastric banding
Gastric bypass
Sleeve gastrectomy- make stomach physically smaller.
What is the resting metabolic rate?
Amount of energy expended at rest
When is RMR higher? Why?
Pregnancy, breastfeeding and obesity.
Why can it be difficult to maintain weight loss?
Adaptive thermogenesis means that BMR cannot fall any further so more difficult to lose weight.
