Obesity Flashcards

1
Q

Obesity

A
  • public health concern and complex social problem
  • being overweight
  • obesity ranks 2nd in the top 10 most common health issue
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2
Q

Social determinants of health (obesity)

A
  • the environments where people are born, grow, live, and work
  • access to medical care and health food, education, housing and transportation, occupation, and job security
  • social determinants combined with health disparities such as environment, socioeconomic status, health literacy, and access to health education may also impact obesity
  • constellation of factors contribute to obesity, including health behaviors, diet, physical inactivity, and genetics
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3
Q

Obesity is a modifiable risk factor

A
  • type II diabetes
  • cardiovascular
  • cerebrovascular
  • gallbladder and liver disease
  • sleep apnea
  • gynecological problems (fibroid disease)
  • neurological (such as atherosclerosis, hypertension, and peripheral vascular disease)
  • musculoskeletal changes like osteoarthritis
  • studies are beginning to look at the relationship of obesity to cancer and Alzheimer’s disease
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4
Q

Metabolic syndrome

A
  • a group of risk factors that increase the likelihood of developing heart disease, diabetes, and other health conditions
  • affects about 1 in 3 adults
    Defined as having at least 3 of the following conditions:
  • abdominal obesity = “apple shape” (or “pear shape” in women)
  • high blood pressure = blood pressure that is 130/85 millimeters of mercury (mm Hg) or higher
  • high blood sugar = a fasting blood sugar level of 100 mg/dL (5.6 mmol/L) or higher
  • high triglycerides = a triglyceride level of 150 milligrams per deciliter (mg/dL) or 1.7 millimoles per liter (mmol/L) or higher
  • low HDL cholesterol = an HDL cholesterol level of less than 40 mg/dL (1.04 mmol/L) in men or less than 50 mg/dL (1.3 mmol/L) in women
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5
Q

Risk factors of metabolic syndrome

A
  • being overweight
  • having an inactive lifestyle
  • family history
  • the more metabolic syndrome risk factors you have, the higher your risk of developing heart disease, diabetes, and stroke
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6
Q

Diabesity

A
  • a term used to describe the combination of obesity and type 2 diabetes (T2DM)
  • is not an official diagnosis
  • it means you have both obesity and type 2 diabetes
  • greatly increases your risk of heart disease (the leading cause of death in the country)
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7
Q

Body mass index (BMI)

A
  • an international standard used to determine degree of obesity looking at weight relative to height
  • BMI can be inaccurate because it does not account for factors like muscle mass, body fat distribution, age, sex, race, and ethnicity
  • ex: someone with a lot of muscle and little body fat can be the same BMI as someone who is obese and has less muscle
  • BMI is a useful screening tool for obesity, but it not a diagnostic tool and should not replace clinical judgment
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8
Q

Waist circumference

A
  • waist circumference plus BMI is used to describe the degree of obesity and predict the level of disease risk
  • indicates the amount of fat distribution in the abdominal area
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9
Q

Bariatic

A
  • a term associated with person who are morbidly obese
  • have a body mass index (BMI) of 35 or higher
  • OR have a BMI between 30 and 35 and an obesity-related condition like heart disease, diabetes, high blood pressure, or severe sleep apnea
  • BMI of 35 or higher = extremely obese
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10
Q

Childhood obesity

A
  • obese children and adolescents are 5 times more likely to become obese adults
  • obesity is defined in children and adolescents aged 2-19 years of age as a BMI at or above the 95th percentile according to gender, age, and growth chart
  • while BMI charts are used to diagnose childhood obesity, caution should be taken
  • BMI results may stigmatize children as being obese and cause issues with self-esteem
  • added psychosocial stress and pressure to be thin (further perpetuated by the media, peers, friends, and family members)
  • dissatisfaction with body image, depression, and failed attempts to achieve weight loss through dieting may result in weight gain, altered metabolic function (insulin sensitivity), and secretion of cortisol
  • combined stressors, obesity, and psychosocial challenges may lower school performance and reduce quality of life
  • BMI results may be used to raise parent and child awareness and discuss and set goals for lifestyle change and weight management
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11
Q

Elder obesity

A
  • obesity among elders may result from a decline in physical activity and a change in independent living
  • more sedentary lifestyle and they are often positioned in and confined to wheelchairs
  • weight gain may be associated with chronic conditions, immobility, and altered eating habits (increased in social eating in nursing homes)
  • limited participation in occupations, deconditioning, and loss of muscle mass (sarcopenia) influences physical function and metabolic rate
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12
Q

Obesity as a disease

A
  • AMA classification of obesity as a disease
  • classifying obesity as a disease raises awareness, increases insurance coverage and reimbursement for treatment, and expands federal and private funding for research, which may lead to new public policies regarding obesity intervention and presentation
  • arguments against this classification = obesity is a risk factor for other chronic diseases, that BMI does not measure fat mass, and that patients diagnoses as overweight or obese may still be healthy
    Disease is defined as:
  • an impairment of the normal functioning of some aspect of the body
  • characteristic signs and symptoms
  • causes harm or morbidity
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13
Q

Obesity and stigma

A
  • weight stigma is defined as “the social rejection and devaluation that accrues to those who do not comply with prevailing social norms of adequate body weight and shape”
  • “obesity as the last socially acceptable form of prejudice”
  • may experience verbal abuse, verbal and physical bullying, poorer care, have worse outcomes, and be more vulnerable to depression, reduced self-esteem and poor self-concept
  • may be perceived as dishonest, sloppy, lacking self-control, lazy, unattractive, intellectually impaired, gluttonous, and socially impaired
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14
Q

Obesity and depression

A
  • medical issue with mental health signs and symptoms
  • the relationship between emotional state, behavior, excessive food intake, and lower energy expenditure may reflect a significant psychosocial issue
  • obese persons have 55% probability of developing depression
  • depression leads to reduced physical activity leads to poor dietary choices leads to obesity leads to inflammation (a continuous cycle)
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15
Q

Obesity and stress

A
  • stress and anxiety may also interfere with one’s ability to lose and manage weight
  • stress results in the secretion of cortisol, which has been shown to increase central adipose tissue and secondary risk factors for disease such as metabolic syndrome
  • cortisol = a hormone that affects many parts of the body, including the immune system, metabolism, and blood pressure
  • chronic stress had a significant effect on food cravings, and food cravings had a significant effect on BMI
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16
Q

Symptoms of high cortisol (obesity and stress)

A
  • disrupted sleep
  • weight gain (in the face or midsection)
  • excessive hair growth
  • sugar, salt, and fat cravings
  • headaches
  • fatigue
  • irritability
  • high blood pressure and blood sugar
  • weak bones
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17
Q

Causes of obesity

A
  • poor diet
  • sedentary lifestyle
  • metabolic factors
  • medications
  • socioeconomic factors
  • environmental factors
  • psychological factors
  • genetics
    Biological:
  • genetics
  • brain-cut axis
  • prenatal determinants
  • pregnancy and menopause
  • neuroendocrine conditions
  • mediations
  • physical disability
  • gut microbiome
  • viruses
    Behavioral:
  • excessive calorie intake
  • eating patterns
  • sedentary lifestyle
  • reduced physical activity
  • insufficient sleep
  • smoking cessation
    Environmental:
  • food abundance
  • built environment
  • socioeconomic status
  • culture
  • bias and discrimination
  • environmental chemicals
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18
Q

Etiology of obesity

A
  • consequence of physical inactivity
  • imbalance between calories consumed and energy expenditure during occupational performance
  • location of grocery stores, food choices, and availability
  • lack of available food resulted in storing fat to prevent starvation
  • type of food (such as fast, convenient, or refined) and high availability result in increased stored fat and the prevalence of obesity
19
Q

Genetic factors of obesity

A
  • genetic factors combined with lifestyle choices increase the risk
  • patterns of childhood obesity are similar in appearance to adult obesity
  • 40-70% of the variance in body mass is related to social environment (type of food consumed, factors, related to heredity, and physical inactivity)
20
Q

Hypothalamus (obesity)

A
  • inability of the hypothalamus to recognize satiety along with thyroid dysfunction may also result in obesity
  • thyroid gland secretes hormone thyroxin into the blood stream that is essential to the regulation of normal body growth and metabolism (processing food into energy)
  • hypothyroidism
21
Q

Hypothyroidism

A
  • occurs when the cells of the thyroid gland are damaged by inflammation
  • results an associated autoimmune response or secondary medical interventions
22
Q

Symptoms of hypothyroidism

A
  • dry hair
  • puffy face
  • goiter
  • slow heartbeat
  • weight gain
  • constipation
  • cold intolerance
23
Q

Obesity and neuroscience

A
  • inconclusive but plausible evidence linking the neurobehavioral effects of overeating, obesity, and addiction
  • addition to food is similar to addiction to drugs both in behavioral and neurological response
  • foods high in fat, salt, and sugar are enjoyed by those who are obese
  • binge eating is characterized by uncontrolled, rapid consumption of large amounts of food in isolation and and in the absence of hunger despite the negative impact on health, social, or financial limitations
  • multiple failed attempts to alter behavior results in feelings of guilt, remorse, distress, and failure
  • impulsive eating or initiating behavior without considering the consequences may be related to lower levels of dopamine
  • insufficient dopamine may increase seeking the feelings of reward and result in overeating
  • the more food that is consumed, the more one loses control and awareness of the amount of food consumed
24
Q

Incidences of obesity

A
  • “globesity”
  • nationally obesity has doubled since 1980
  • preschool = 8.9%
  • school children = 17.5%
  • adolescents = 20.5%
  • young adults = 32.3%
  • middle adults = 40.2%
  • older adults = 37%
25
Q

Obesity and lymphedema

A
  • obesity can cause compromised skin integrity, secondary to skin-on-skin contact and impaired lymph drainage
  • a BMI greater than 50 (255 lbs at 5’ and 368 at 6’) often results in bilateral lower extremity edema associated with lymphatic dysfunction
  • adipose tissue is composed of adipocytes or fat cells that produce hormones referred to as adipokines
  • adipokines cause a chemical reaction that impedes the function of the lymph system, causing lymphatic leakage or lymphedema (swelling)
  • obesity combined with decreased muscle pumping action further limits lymphatic function
26
Q

Obesity and arthritis

A
  • increased joint stress
  • inflammation
  • accelerated degeneration
  • a reduction of weight by 10 points and achieving a BMI within the recommended normal range would result in an estimated 50% reduction in knee surgeries associated with OA
27
Q

Increased joint stress

A
  • obesity significantly increases stress on weight bearing joints (like knees, hips, and spine)
  • for every one pound of excess weight, an additional 4-5 points of pressure is exerted on the knee joints
28
Q

Inflammation (obesity)

A
  • obesity is associated with systemic inflammation due to excess fat tissue, which releases pro-inflammatory chemicals
  • can exacerbate joint inflammation in arthritis
29
Q

Accelerated degeneration

A
  • in OA, obesity can lead to faster degeneration of cartilage, particularly in the knees
  • inflammatory arthritis (like RA) may also be worsened by obesity-related inflammation
30
Q

Obesity hypoventilation syndrome

A
  • also called as sleep apnea
  • excess weight compressing on the chest, preventing breathing, and increasing the amount of carbon dioxide in the blood
  • lack of oxygen contributes to poor quality of sleep and hypoxia
  • as weight increases around the neck, trunk, and abdomen, it temporally lapses in breathing, compromising respiratory function
  • continuous positive airway pressure (CPAP) may be used to achieve positive flow of air into the nasal passages in order to keep the airway open
31
Q

CPAP machines

A
  • continuous positive airway pressure
  • used to achieve positive flow of air into the nasal passages in order to keep the airway open
    Types of CPAP masks:
  • nasal mask = covers nose
  • full face mask = covers nose and mouth
  • nasal pillow = tubes fit into the nostrils
32
Q

Diets to address obesity

A
  • Atkins diet = low-carbohydrates, high-protein diet that burns fat for fuel (side effects = reduced brain glucose and increased blood lipid levels)
  • South Beach diet = (supported by research) balances carbohydrates, protein, and fat; does not limit fruits and vegetables which is a disadvantage for maintaining a restricted pattern of eating
  • Zone diet = requires 30% of each fat, protein, and carbohydrates and focuses on health grains and fiber
  • Body for Life program = encourages 6 small meals per day to maintain stable blood sugar
  • Weight Watchers = (well-research) uses a point system, a balanced meal plan, and a support group or online participation
  • Noom = combines a behavioral approach with a custom diet based on body type; weekly virtual coaching appointments, supports health and fitness, and lone-term weight-loss
33
Q

Weight loss drugs

A

GLP-1 agonists (Semaglutide, Liraglutide)
- ex: Wegovy, Ozempic, Saxenda
- how they work = these drugs mimic the hormone GLP-1, which regulates appetite and insulin (slows down digestion, making people feel full longer, which helps reduce caloric intake_
- effectiveness = clinical trials have shown significant weight loss in individuals who use GLP-1 agonists in conjunction with lifestyle changes
- common side effects = nausea, vomiting, diarrhea, and constipation
Tirzepatide (Mounjaro)
- how it works = a dual GIP and GLP-1 receptor agonists that regulates blood sugar and reduce hunger which promotes weight reduction (has shown promise for both type 2 diabetes management and weight loss in obese individuals)
- effectiveness = studies have shown weight loss in the range of 15-20% of body weight for some individuals using Tirzepatide

34
Q

Thoughts of weight loss drugs

A
  • Wegovy and Ozempic are not for everyone. Ozempic is approved for people with type 2 diabetes and Wegovy is approved for people with obesity or those who are overweight and have health problems related to excess weight.
  • If you lose weight with new drugs, you will likely need to keep taking the medications forever to keep the weight off. People who stop taking Wegovy and Ozempic often gain weight back relatively quickly.
  • The drugs are expensive and in general insurance plans don’t cover them for weight loss (although they often do for people with diabetes).
  • the popularity of the new drugs had led to some shortages
  • the drugs can cause unpleasant gastrointestinal side effects
  • A small percentage of people who take the drugs can suffer from a diabetes eye complication called retinopathy. Along with consulting with your primary care provider or endocrinologist, you should also see your eye doctor.
  • The drugs tend to suppress a person’s appetite but to lose weight, you’ll still need to reduce your intake of desserts, sugar-sweetened beverages and fatty foods. And of course, exercise is important to keep your body healthy.
  • Some people have complained about looking older due to “Wegovy or Ozempic face”. While many people taking weight loss drugs are pleased to shed some points, some say they’re dropping weight in the wrong place like their face. Some have complained of looking old and gaunt due to fat loss in the face.
  • you may lose up to 40% of your muscle mass while taking weight loss drugs
35
Q

Bariatic surgery

A
  • adjustable gastric band
  • gastric bypass
  • sleeve gastrectomy
36
Q

Gastric bypass (Roux-En-Y)

A
  • weight loss = rapid initial weight loss
  • length of stay = 2.5 days
  • recovery time = 18 days
  • reversibility = not easily reversed
  • nutrient absorption = some minerals not easily absorbed
  • risk of complications = moderate
  • procedure = this surgery involves creating a small pouch from the stomach and connecting it directly to the small intestine (the food bypasses most of the stomach and the upper portion of the small intestine, reducing the calorie absorption)
  • benefits = leads to significant weight loss, reduces appetite, and can improve conditions like type 2 diabetes
  • risks = potential for malabsorption, dumping syndrome, and nutritional deficiencies
37
Q

Sleeve gastrectomy

A
  • weight loss = rapid initial weight loss
  • length of stay = 3-4 days
  • recovery time = no data yet
  • reversibility = non-reversible
  • nutrient absorption = not affected
  • risk of complications = 17.1% experience at least one complication
  • procedure = about 80% of the stomach is removed, leaving a tube-shaped portion or a “sleeve” (this smaller stomach limits the amount of food intake and reduces hunger by lowering ghrelin hormone levels
  • benefits = effective weight loss, simpler than gastric bypass, and less risk of nutritional deficiencies
  • risks = irreversible and potential complications like leakage, acid reflux, or nutrient deficiencies
38
Q

Adjustable gastric band (Lap-band)

A
  • weight loss = 55% excess weight loss (5 years)
  • length of stay = discharged same day as the surgery
  • recovery time = 7 days
  • reversibility = band can be removed easily
  • nutrient absorption = not affected
  • risks of complications = low
  • procedure = a silicone band is placed around the upper portion of the stomach, creating a small pouch (the band can be adjusted to control the amount of food the stomach can hold, helping to reduce food intake)
  • benefits = the band is adjustable and reversible, involves less invasive surgery
  • risks = weight loss is generally slower compared to other procedures and complications like band slippage or erosion may occur
39
Q

Occupational implications on ADLs (obesity)

A
  • mobility = reduced mobility and difficulty performing basic tasks like walking, getting in and out of the bed, or climbing stairs, which may impact personal hygiene, dressing, and toileting
  • self-care = larger body mass may make self-care tasks such as bathing, grooming, and dressing more challenging, particularly for areas of the body that are difficult to reach
40
Q

Occupational implications on IADLs (obesity)

A
  • household management = tasks such as cleaning, cooking, and shopping may be more physically demanding due to the increased weight, fatigue, or limited endurance
  • community participation = social isolation may occur due to the physical limitations or stigma associated with obesity, impacting community engagement, leisure activities, and transportation
41
Q

Occupational implications on work and productivity (obesity)

A
  • workplace limitations = some jobs may require physical abilities (ex: lifting, standing for long periods) that may be difficult for individuals with obesity (can lead to decreased productivity or an increased risk of injury
  • ergonomic challenges = standard equipment (chairs, desks, tools) may not accommodate the physical needs of individuals with obesity, causing discomfort and decreased occupational performance
42
Q

Occupational implications on leisure and social participation (obesity)

A
  • reduced engagement in physical activities = due to limited mobility, pain, or fatigue, individuals with obesity may avoid leisure activities that require physical exertion, limiting opportunities for physical exercise and enjoyment
  • social barriers = the stigma and discrimination associated with obesity can lead to social withdrawal and reduced participation in community or group activities, impacting mental health and well-being
43
Q

Occupational implications on psychological and emotional impact (obesity)

A
  • body image and self-esteem = obesity is often associated with negative body image, which can contribute to lower self-esteem and impact motivation to engage in various occupations
  • mental health = there is a known correlation between obesity and mental health conditions such as depression and anxiety, which can further limit occupational performance and participation
44
Q

Occupational implications on health management (obesity)

A
  • chronic conditions = obesity is often linked with comorbid conditions like diabetes, cardiovascular disease, and joint pain (ex: OA), requiring ongoing medical management, which can interfere with other daily activities and work routines
  • energy conservation = the physical demands associated with obesity may lead individuals to engaged in compensatory strategies such as pacing, use of adaptive devices, or the delegations of tasks to conserve energy