Nutrition and Pregnancy Flashcards
significant increase in DNA content (cell number) before birth (undernourished children had decreased increase), levels off after birth; Protein content (cell size) continually increases before and after birth
Human brain
Liver increases throughout life, Kidney increases after birth but stops at about 3-4 months
Tissue DNA content (cell size)
->only carbohydrate transported across the placenta by facilitated diffusion
(concentration greater on the mother’s size)
Glucose
- > transported as acetyl CoA and free FA across the placenta
- > species differences in ease of transport
-> in humans the main source of this for fetuses is glucose
Fat
-> cross by pinocytosis
(small section of maternal cells is swallowed into vacuole and released into cell on fetal side)
-> the rate is inversely proportional to square root of MW for:
~albumin
~fibrinogen
~gamma-globulins
~transferrin
-> GH, insulin and TSH DO NOT cross (protects)
-> fetus gets 10-15% of daily requirement from drinking amniotic fluid
(fetuses with swallowing difficulties suffer growth retardation)
Proteins
> cross by active transport
- > concentration is highest on fetal side
- > only L type cross, NOT D
AA
more surface area causes increased weight of fetuses -> obese mothers have highest placental weight
Placental size
the fattest fetus at birth of all species
Humans
first the mother increases levels, fetus will increase levels after a delay then exponentially
Fat
5g more protein, 0.8MJ more energy 30mg more of ascorbic acid, 700mg more of calcium, 3 more mg of iron
Daily dietary requirements for pregnancy in 3rd trimester
actually need more than during pregnancy of protein and energy (same for ascorbic acid, calcium and iron)
Lactation
optimal BMI for conceiving children
20-26
key to pregnancy nutrition -> basic principles during pregnancy are the same -> it is likely to provide the micronutrients needed, it should include enough portions of fruits and vegetables
Eating a balanced diet
no increase in the first trimester -> 300 increase per day in 2nd and 3rd trimester, increase should come from nutrient dense foods -> need for increase depends on physical activity, age and weight
Calories
most of the energy will come from this source, mostly complex starch -> whole grain foods are good because they are high in B vitamins and high in trace minerals such as zinc, selenium, chromium, magnesium
Carbohydrates
required for hyperplasia and hypertrophy of maternal tissues and to meet fetal needs
- > intake for pregnancy is about 70 g/day
- > greatest demand during the last half of pregnancy when the fetal growth is greatest
Protein