Nursing Considerations: Antifungals/ Antituberculars Flashcards
1
Q
- Monitor liver function
- Monitor for elimination of s/s TB – productive cough, fever, night sweats).
A
Anti-tubercular Drugs
2
Q
May need to do “direct observation” to confirm patient takes med. Weekly pill counts are another way to track compliance with med regimen.
A
Anti-tubercular Drugs
3
Q
- Strict adherence to med regimen to preview development of drug resistance.
- Avoid alcohol to decrease risk of liver problems.
- Avoid foods with tyramine
- Drug may decrease effectiveness of oral contraceptives.
A
Anti-tubercular Drugs
4
Q
- Check for history of renal disease – special formulation available or those with kidney disease or another antifungal could be used.
- Electrolytes – Potassium, Calcium, Magnesium
- Kidney Function – BUN, CR, GFR CBC
- Urine output – amount, color
A
Polyenes
5
Q
- Hydrate before infusion to protect kidneys
- Administer premedication as ordered – steroid, antihistamine, and acetaminophen typically.
- Be clear that “amphotericin B” and “amphotericin B liposomal” ARE NOT Interchangeable.
- Administer IV over several hours and check vital signs per protocol.
A
Polyenes
6
Q
Report tinnitus, hearing loss, vertigo – may be due to ototoxicity.
A
Polyenes
7
Q
Infuse slowly to avoid cardiovascular collapse
A
Polyenes (anti-fungal)
8
Q
Confirm not pregnant
Check for history of liver disease
A
Triazole Drugs (anti-fungal)
9
Q
- Report s/s liver dysfunction including unexplained bruising or bleeding.
- Report skin rash, unexplained fever, diarrhea.
A
Triazole Drugs (anti fungal)
10
Q
Polyenes
BUN > ______
Cr > ______
A
BUN 40
Cr 3
