Nurb Test 4: cancer medications Flashcards
-(cell cycle non-specific) breaks DNA strand which interfers with DNA replication. Breaks in different areas
Alkylating agents
Alkylating agents
carboplatin
cisplatin
dacarbazine
mustargen
-used for ovarian, lung, BMT
Alkylating agents
Carboplatin
-used for ovarian, breast, bladder, Hodgkins and non Hodgkins. (possible vesicant)
Alkylating agents
Cisplatin
-Hodgkins, soft tissue sarcoma (irritant) can go peripheral line but slow, watch line/ port or central line use
Alkylating agents
Dacarbazine
-used for Hodgkins and non-Hodgkins (vesicant)
Alkylating agents
Mustargen
-(cell cycle specific) inhibits an enzyme production for DNA synthesis
Antimetabolite
Antimetabolite
Xeloda
5fu
gemzar
-oral medication for metastatic colon cancer and breast cancer. Make sure that they are compliant
Antimetabolite
Xeloda
-used colorectal, breast, liver, ovarian, and pancreatic cancers. (irritant) given peripheral watch line
Antimetabolite
5FU
-gold standard for pancreatic= prolong life, breast, ovarian, small and non-small cell lung cell (possible vesicant) give through port
Antimetabolite
Gemzar
- (cell cycle non-specific) binds with DNA inhibiting DNA and RNA synthesis
Antitumor Antibiotic
Antitumor Antibiotic
Adriamycin (Doxorubicin)
Bleomycin
- used for breast, prostate, ovarian, stomach, small-cell lung, and liver cancers ( true vesicant) * always have a port or central venous access
- red devil makes urine red, run with another iv like normal saline, so its not totally red it is a pink color
- will lose hair, become nausea pee red or pink 3-5 days
Antitumor Antibiotic
Adriamycin (Doxorubicin)
-used for Hodgkins and no, inject into pleural cavity-Hodgkins, malignant pleural effusion , can’t have any more fusions because scaring ( vesicant)
Antitumor Antibiotic
Bleomycin
-(cell cycle specific) inhibits DNA production and preventing cell division.
Plant Alkaloids
-used for Hodgkins, testicular cancers, Kaposis sarcoma( possible vesicant) central venous access
Plant Alkaloids
Vinblastine
Biotherapeutic types
interferons
interleukins
monoclonal antibiodies
-inhibits DNA and protein synthesis in tumor cells and increases the immune response against the tumor cell.
Biotherapeutic
Interferons
-activation of the immune system. This is in clinical trials now.
Biotherapeutic
. Interleukins
-binding specific target cells in DNA, take some cancer cells out during biopsy then mix with it, then give antibodies goes to tumor cells and stops production, only goes to tumor cells doesn’t go to normal cells, mot used widely bc still under research
Biotherapeutic
Monoclonal Antibodies
