Nurb Test 2: Bone and joint disease Flashcards
- can be asymptomatic= hard mass,
- can affect your height bc on growth plate, could experience muscle soreness with exercise
- shortened extremity on affected side
Osteochondroma
Clinical Manifestations
Benign and malignant
Rare in adults
Named according to are of the bone and tissues affected and type of cells that form the tumor
bone tumors
- asymptomatic don’t do anything
Can have surgically receipted, if all the cartilage cap is removed it will not come back
Monitor so it does not become malignant
tx osteochondroma
- cancerous, extremely aggressive, metasis 10-20% to other sites most common are the lung
- happens in children or young adults
if happens over 60 it is secondary bc pagets disease
Osteogenic Sarcoma
Malignant Bone Tumor
- large bones with fastest growth rate, proximal tibia: below the knee, distal femur=above the knee, proximal humorous, pelvis
locations osteogenic sarcoma
pain and swelling gradually, notice a lot around the knees, restricted range of motion if around a joint,
Minor injury could not cause this but can help it to be found
Manifestations:
osteogenic sarcoma
- xray, ct, mri,
- biopsy of tissue, increase serum alkaline phosphate= bc produced in bone cell, calcium level increased, pet scan- radioactive material will show higher areas of acitivity
dx osteogenic sarcoma
- aimed at quality of life
- amputation: follow up with chemo to give better survival rate
- limb spearing surgery: start chemo before to shrink the tumor
tx osteogenic sarcoma
Spread From Primary tumor-comes from another tumor
Metastatic Bone Cancer
breast, prostate, lungs, kidneys, ovaries, thyroid, GI
sites metastatic bone cancer
Travel through lymph and blood supply moves to other sites: pelvis, vertebral, humorous, femur, ribs
metastatic bone cancer
____fx bc weakening of bone
Increased serum calcium= bc ca released from bones that is damaged
pathological
manifestations of metastatic bone cancer
- bone scan= after find primary lesion
dx metastatic bone cancer
- palliative= comfort, radiation, pain management , fx can have surgery
tx metastatic bone cancer
:Open wound
Foreign body: implant, plates, prosthetic device
Direct entry
osteomyelitis
- infection somewhere else then migrates to the bone
Indirect entry
osteomyelitis
Abscess, sickle cell anemia, diabetes mellitus, tb
Vascular insufficiency- pelvis, tibai, vertbrea
Urinary
Respiratory
causes
osteomyelitis
Invasion of pathogen Inflammatory process Edema- increase pressure Ischemic necrosis- bone dies Sequestrum
PATHOPHYSIOLOGY
osteomyelitis
becomes an island of dead bone, seperated by puss, white blood cell can’t reach, hard to treat, Site for microorganisms to spread to lung and brain , can move out of the bone to soft tissue
Sequestrum-
- Removed by normal immune process if acute
- Removed by surgical debridement
- New bone grow around it =involucrum
- If not heal trap cab form abd puss can escape
- Typically you have exacerbations, May develop into chronic site- scar tissue can dev and it is harder to get rid of
tx sequestrum
– Infection of <1 month in duration
Acute Osteomyelitis
: fever, night sweats, chills, restlessness, nausea
Systemic Sx
acute osteomyelitis
: constant pain worse with activity not better with rest, swelling, tenderness, warmth at site, could have restricted mov
Local sx
acute osteomyelitis
Later sign: drainage
acute osteomyelitis