Nurb Test 1: Delirium and Dementia Flashcards
-progressive loss of consciousness
- Dementia
Cognitive Problems
Three most common in adults
dementia
delirium
depression
- Often associated with dementia and delirium
- Depression
—acute confusion, rapid, can be reversed
- Delirium
- State of temporary but acute mental confusion, always secondary to another condition
- Highest in hospitalized older adults, 40% in icu
- sudden cognitive impairment, disorientation, sensory
Delirium
: Lung, Heart, Infection, Poor nutrition, Drug interactions
delirium Co morbidities
: Longer hospitalization, frequent high misdiagnosis leading to high death rate, further functional decline, Institutionalization
delirium Risk for
misunderstood Rarely caused by a single factor
- Chronic stress, Cholinergic deficiency, Excesses relief of dopamine - Often caused by an underlying factor usually precipitating event happens
delirium Contributors:
A. Demographics: 65 or older, male
B. Cognitive status: dementia, cognitive impairment, and hx of delirium
C. Environmental: admit to icu, use of physical restraints, pain= become aggressive, emotional stress, sleep deprivation
D. Functional: immobility, hx of falls
E. Sensory: overload, deprivation
F. Decreased oral intake: dehydration, malnutrition
G. Drugs- 4 or more, sedatives, opiates, drug interactions, alcohol, drug withdraw
H. Surgery
I. Co-existing medical conditions: acute or terminal illness, hx of stroke, infection or sepsis, or any neurological disease
Delirium Precipitating Factors
- two to three days, rapid
Delirium Clinical Manifestations
Onset
- can last 1-7 days, can be discharged with
delirium Duration
- after two to three days, agitation, misperception, hallucinations
Later sx delirium
-Irritability, restless, confused, can’t concentrate
early sx delirium
- Medical history: family can provide
- Physical exam
- Psychological history
- Medications: new ones put on
- Cognitive measures: mmse: mini mental state examination= what cows drink
- Laboratory tests: electrolytes, bun, creatinine,
- Any preexisting: drug and alcohol levels, liver analysis
Delirium Diagnostic Studies
- When did the confusion begin?
- Does the condition change over a 24-hour period?
- Is there a change in the person’s sleep patterns?
- What specific thought problems have been noticed?
- Is there a history of mental illness or similar thought disturbance?
- Has there been a sudden decline in physical function or a new onset of falls?
Delirium Critical Questions to ask the patient
prevent , early recognition, treatment as necessary
- Focus on eliminating precipitating factors: protect from harm no falls, encourage family to stay at bedside and be involved
- If secondary to infection, antibiotic therapy is started
- Reorientation and behavioral interventions—used in all patients: create safe enviro, don’t overstimulate, reassure the patient and family, pay attention to noise level
- Safety is number one!
Delirium Nursing Management
Nurse’s role:
Delirium Drug Therapy- Reserved for those patients with severe agitation
low dose antipsychotics
short acting benzodiazepine
B. Short-acting benzodiazepines
- lorazepam [Ativan]
A. Treated with low-dose antipsychotics
- Haloperidol (Haldol) 2. Risperidone (Risperdal) 3. Olanzapine (Zyprexa) 4. Quetiapine (Seroquel)
- irreversible, not caused by any other disorder
- Vascular dementia (VD) 20% (multiinfarct)
- Alzheimer’s disease (AD) 60%
A. Primary dementia
due to another condition can reverse if find the cause, if they keep being exposed (prolonged) to these it can make it irreversible
Ex: AIDS dementia complex, Korsakoff’s syndrome=vit B deficiency associated with heavy alcohol consumption, infection
B. Secondary dementia
- Onset of depends on cause
- gradual and progressive
- abrupt step by step pattern
- Etiology of difficult to distinguish based on symptoms alone
Dementia Assessment Clinical Manifestations
Neurological
Vascular
function normal, can do adls, do have memory loss, mild disorientation, words become difficult to find, difficulty with numbers, lose interest in hobbies -still with it enough can compensate, hard to diagnose, ongoing eval
mild dementia
start to lose recognition of family and friends, agitated, pace, wonder get lost more frequently, loss of ability to do skills, argue easily, hallucinations occur
moderate dementia
little memory left, don’t recognize self in the mirror, cant process new info, cant process words, eating and swallowing is difficult, repeat words, can’t perform and adls, become immobile and incontinent
severe dementia
- Try to find cause to see if it is irreversible
- Thoroughly evaluate patient history-anything can treat
- Physical examination to rule out other medical conditions
- Screening
- Mental status testing (MMSE)
- Functional Screening
- Depression screening because it happens with dementia a lot : look at if fatigued, how active are they, appear to be very sad, difficulty concentrating or thinking
- Do an ongoing assessment, find pt is at risk= monitor closely do mri and ct to see changes
dementia dx studies
A. =basic adls, bathing dressing, toileting, eating,
katz
=more complex adls: grocery shopping, cleaning house, cooking, paying bills
lawtons
scores the functions of eating dressing, habit changes
C. Blessed Dementia rating scale:
-Exact is unknown what triggers
-Similar to other forms of dementia, hard to distinguish
-Age is most important risk factor
Early onset= less than 60 years old
Alzheimer’s Disease Etiology
: in genes, earlier onset, more rapid
Familial Alzheimer’s disease
Not in genes
-Sporadic Alzheimer’s:
-Pathologic changes precede clinical manifestations by 5 to 20 years, brain is changing but no signs and symptoms
-Changes in brain structure and function
A. Amyloid plaques: plaques dev as we age, more than norm in hippocampus= short term memories are
B. Neurofibrillary tangles: twisted proteins in the nerves
C. Loss of connections between cells and cell death: parts of your brain
Alzheimer’s Disease Pathophysiology
- Diagnosis of exclusion
-No single clinical test
-Made once all other possible conditions causing cognitive impairment have been ruled out
-Comprehensive patient evaluation: Complete health history, Physical examination, Neurologic assessment, Mental status assessment, Laboratory tests
-Brain imaging tests
CT – Computed Tomography
MRI – Magnetic Resonance Imaging
PET – Positron Emission Tomography- active cells are yellow
*Allow monitoring in early stages and treatment response
Alzheimer’s Disease Diagnostic Studies