Nucleic Acids Flashcards

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1
Q

what are molecules?

A

molecules → make up → gentic material → all living things

“building blocks of life”

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2
Q

what is a nucleotide?

A

A nucleotide is the basic building block of nucleic acids (RNA and DNA). A nucleotide consists of a sugar molecule (either ribose in RNA or deoxyribose in DNA) attached to a phosphate group and a nitrogen-containing base.

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3
Q

what his a nucleotide made up of?

A

phosphate, sugar, nitrogenous bases

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4
Q

what are the two types of nucleic acids?

A
  • DNA (deoxyribonucleic acid)
  • RNA (ribonucleic Acid)
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5
Q

what is the purpose of sugar in a nucleotide?

A

the sugar creates a strong bond with phosphate, creating the sugar-phosphate backbone

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6
Q

what is the purpose of nitrogen bases in a nucleotide?

A

the nitrogen base projects off the sugar to create a site ready for binding

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7
Q

What is condensation polymeriastion?

A

It is a form of a step-growth polymerization where smaller molecules or monomers react with each other to form larger structural units (usually polymers) while releasing by-products such as water or methanol molecule.

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8
Q

how are the four bases bonded?

A

bases are bonded using a weak hydrogen bond

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9
Q

what are the four bases?

A

Cytosine, Guanine, Adenine, thymine Uracil ( only for RNA)

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10
Q

What are the two base pairs

A

1) AT Adenine, thymine
2) GC Cytosine, Guanine

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11
Q

Where is the base Uracil found?

A

RNA strand

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12
Q

Because DNA is like a long piece of very fine string, it is important it doesn’t tangle or break. In order to keep the DNA from tangling, a molecule called a ______ is used.

A

nucleosome

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13
Q

what is a nucleosome?

A

A nucleosome is compromised of 8 proteins called histones which clump together. DNA wrap 1 3/4 times around these histones, providing order and structural integrit. (meaning doesn’t tangle of break.

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14
Q

what is a histone?

A

A type of protein found in chromosomes. Histones bind to DNA, help give chromosomes their shape, and help control the activity of genes.

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15
Q

what is DNA

A

DNA is the collection of nucleotides that makes up genes and chromosomes.

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16
Q

What are Genes?

A
  • Genes are segments of DNA that tell the body how to express (show) something.
  • For example, there is a gene that tells your body what colour to make the iris in your eyes. (There’s actually a few genes which do this).
17
Q

What are chromosomes?

A
  • A chromosome is made up of the entire strand of DNA, which is comprised of many genes. So a chromosome is represented by the entire image to the right.
  • In nature there are two main types of chromosomes: prokaryotic chromosomes and eukaryotic chromosomes.
18
Q

what are prokaryotic chromosomes?

A
  • Prokaryotes do NOT have a nucleus. So instead of having their chromosomes encased inside of a nucleus, they have a single chromosome which floats freely around the cell.
  • Prokaryotic DNA is:
    • Circular, double stranded
    • Not bound to histone proteins
19
Q

mitochondrail and chloroplast DNA

A
  • Mitochondria and Chloroplasts also have genetic material stored within them.
  • The DNA found in these organelles is very similar to prokaryotic DNA and supports the theory of endosymbiosis (the idea that mitochrondria was taken into another cell in a mutualistic relationship)
20
Q

what are eukaryotic chromosomes?

A
  • Eukaryotic chromosomes are located in the nucleus and are mostly found in pairs. (There are some species which are exceptions).
  • In humans (and many plants and animals) chromosomes are passed on to offspring via sexual reproduction.
  • In this case, one set of the pair of chromosomes comes from the father and the other from the mother.
  • So one ‘Chromosome 1’ (see left) comes from Dad and the other comes from Mum- it is the same for the other 22.