NT expl Sz Flashcards
1
Q
What does NT explanation for sz say
A
- NT imbalance in synapse (high dopamine activity) causes positive symptoms
2
Q
What receptors link to Sz
A
D2
3
Q
What causes positive symptoms in NT explanation for Sz?
A
High activity in mesolymbic
4
Q
What causes negative symptoms in NT explanation for Sz?
A
Low activity in mesocortical
5
Q
What other NTs link to Sz?
A
- Low glutamate (as it influences dopamine) may cause psychosis
- High serotonin can cause pos or neg symptoms
6
Q
Supporting for Sz & NT
A
- Seeman = higher number of D2 receptors
- Lindstroem = use L-DOPA faster
7
Q
Conflicting for Sz & NT
A
Depatie = drugs that increase dopamine do not cause symptoms of Sz
8
Q
Non bio explanation for Sz
A
Cognitive explanation
9
Q
Key ideas of cognitive explanation for Sz (4)
A
- Hallucinations caused by sensory overload (do not filter out background noise etc)
- Dopamine can cause hallucinations, disorganised thinking is trying to make sense of them
- Confusing inner voice as external
- Poor link between memory & schema -> disorganised thinking
10
Q
Sz cognitive explanation supporting
A
Mcguire found on brain scan same area activated for inner speech & auditory hallucinations
