Genetic Expl Of Sz

Question 1

How much does risk increase if an MZ twin of Sz?

Answer 1

1% -> 48%

Question 2

What chromosomes could cause sz?

Answer 2

• C4-A
• Chromosome 5

Question 3

What could genetic differences do?

Answer 3

• change brain functioning
• alter function of synapse
• may have been evolutionary

Question 4

Sz Genes supporting

Answer 4

• Kety = 8.7% vs 1.9% sz in bio fam of sz vs control
• Gottesman = 1->48% MZ

Question 5

Sz genes face validity

Answer 5

Explains why it runs in families

Question 6

Genes Sz conflicting

Answer 6

Tamminga = cannot pinpoint single gene

Question 7

Twin studies weakness (environment)

Answer 7

E.g gottesman, assume same environment grew up in, may not be true