Antidepressants Flashcards

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1
Q

What type of drugs are antidepressants

A

Monoamine agonists

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2
Q

Types of antidepressants & how they work

A
  • SSRIs = inhibit reuptake of serotonin -> more in synapse to bind to receptors
  • Tricyclic = work on all 3 but rarely used now
  • MAOIs = stop MAO so more monoamines to bind
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3
Q

Supporting for antidepressants

A
  • Aroll found antidepressants more effective than placebo
  • Royal College of Psychiatrists found 65% improve
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4
Q

Conflicting for antidepressants

A
  • Weich = as few as 30% take them
  • Jarrett = MAOIs have toxic effects when combined w food, drink, other drugs
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