Bio Expl Of Sz

Question 1

What causes Sz (NTS)

Answer 1

Excess activity at D2 receptors
- High mesolymbic = positive symptoms
- Low mesocortical = negative symptoms

Question 2

Glutamate? (NTs)

Answer 2

• Low glutamate may cause as mediates dopamine

Question 3

What NTs for Sz does ignore?

Answer 3

Environment eg childhood trauma

Question 4

NTs for Sz C&E

Answer 4

No cause & effect -> Sz may cause high D2

Question 5

NTs for Sz useful?

Answer 5

• Useful for drug treatmens eg antipsychotics like dopamine inhibitors
• But drugs do not work for everyone

Question 6

NTs for Sz supporting

Answer 6

• Seeman = more D2 receptors in SZs
• Lindstroem = SZs use L-DOPA faster than controls

Question 7

NTs for Sz conflicting

Answer 7

• Depatie = found giving people drugs that increase dopamine does not increase symptoms of sz