Bio Expl Depression

Question 1

Biological explanation of depression

Answer 1

Low monoamine levels
- Could be high MAO
- Could be excess reuptake
- 5HTT Gene = less serotonin when stressed

Question 2

What gene links to depression?

Answer 2

5HTT
- low serotonin when stressed

Question 3

How do the different NTs link to depression?

Answer 3

• Low Dopamine = lack of motivation, lack of concentration
• Low Noradrenaline = lack of energy / change in sleep
• Low Serotonin = low mood, sleep issues

Question 4

Supporting for bio explanation of depression

Answer 4

• Bell = depleted levels of tryptophan (serotonin) cause symptoms
• Drevets = Reduced potential for serotonin to bind to receptors

Question 5

Conflicting for bio explanation of depression

Answer 5

• Delgado = monoamine depletion did not make symptoms worse
• Perez = Mice without tryptophan not depressed

Question 6

What amino acid links to serotonin

Answer 6

tryptophan