Carlsson Flashcards
1
Q
Carlsson aim
A
Do NTs other than dopamine cause depression?
2
Q
Carlsson - how many reviewed & what types
A
32 studies
- Animal
- Brain Scans
- Drugs eg PCP
- People with parkinsons
3
Q
Results for Carlsson
A
- Dopamine hypothesis is too simplistic
- Low glutamate increases dopamine
- NDMA antagonists (like PCP) also affect serotonin- could be involved
- Clozapine highly effective as lowers dopamine & serotonin
4
Q
Which drug lowers dopamine & serotonin in carlsson?
A
Clozapine