Carlsson Flashcards

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1
Q

Carlsson aim

A

Do NTs other than dopamine cause depression?

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2
Q

Carlsson - how many reviewed & what types

A

32 studies
- Animal
- Brain Scans
- Drugs eg PCP
- People with parkinsons

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3
Q

Results for Carlsson

A
  • Dopamine hypothesis is too simplistic
  • Low glutamate increases dopamine
  • NDMA antagonists (like PCP) also affect serotonin- could be involved
  • Clozapine highly effective as lowers dopamine & serotonin
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4
Q

Which drug lowers dopamine & serotonin in carlsson?

A

Clozapine

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