Normal Microbiota Flashcards
Which part of our body does not have normal microbiota flora?
lungs
What are the major sites of colonization for microbiota?
GI tract, mouth and upper respiratory, skin, and urogenital tract
How do colonizers get in body?
- usually from the skin (in the birth canal)
- maternal milk also has microbiota
What can happen due to disruption of early microbiota?
allergy, asthma, and obesity
Roughly, how do the patterns of colonizers arrange through the intestinal tract?
stomach= usually 1 colonizer
small intestine= low number
large intestine= high numbers
What are the 2 most abundant bacteria in the intestines?
Bacteroides (30% and gram - rod)
clostridium (gram + rod)
- both strict anaerobes
What is the major role in the gut of bacteroides?
break down plant glycans/carbohydrates
What is the most abundant species of bacteria in the human gut?
bacteriodes thetaiotaomicron
What important oral microbiota were once thought to be bacteriodes?
prevotella and poryphromonas
Which bacteria are periodontal relevant bacteria?
- porphyromonas gingivalis
- tannerella forsythia
- treponema denticola (spirochete)
Which bacteria are ulcerative gingivitis relevant bacteria (before periodontitis)?
- treponema denticola (spirochete)
- fusobacterium
- prevotella
What are the abundant types of bacteria in the mouth?
- streptococcus (mutano,oralis)
- many obligate anaerobes
- diphtheroids
- lactobacillus
- neisseria
What are the predominant flora found in the upper respiratory tract?
- streptococcus (pneumonia, mitis, etc)
- haemophilus
- neisseria and mortaxella
- staphylococci (s. aureus in the nose)
- aerobic diphtheroids
- mycoplasma
similar to mouth
What are the predominant flora found in the lower respiratory tract?
transient only
What are the predominant flora found in the skin?
aerobic gram + cocci:
staphylococcus epidermidis, micrococcus, staph aureus from nose
diphtheroids:
corynebacterium, propionibacterium in hair follicles causing acne
sometimes strep. pyogenes in kids which are 10% carriers
What is the aerobic diptheroid found in skin?
corynebacterium (harmless)
What is the anaerobic diptheroid found in skin?
propionibacterium acnes (grows in hair follicles and when inflamed, cause acne)
What are the common sites of colonization in the genitourinary tract?
epithelial surface of anterior urethra, vagina, and cervix
Who is more likely to get a UTI?
women are 10x more common in getting a UTI due to anatomical differences (length) than men
What are the common bacteria found in vagina/cervix?
- lactobacillus
- intestinal bacteria: streptococci, E. coli, intestinal anaerobes
- skin bacteria: staphylococci and diphtheroids
T/F: There are more microbiota bacteria than your own body cells.
True!
