B-hemolytic Streptococci Flashcards

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1
Q

What do staph. aureus and strep. pyogenes have in common?

A

they are both gram + cocci

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2
Q

How does streptococcus grow?

A

chains
(from humans)

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3
Q

Do streptococci use oxygen?

A

not necessarily- they can tolerate low oxygen though

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4
Q

What is most common strep. in strep throat, necrotizing fasciitis, rheumatic heart disease, and scarlet fever?

A

Group A = S. pyogenes
most important B-hemoltyic strep

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5
Q

What is the most common strep in upper respiratory problems?

A

mitis- s. pneumonia
most common meningitis

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6
Q

What is the most common strep in dental caries and periodontal disease?

A

mutans- s. mutans and s. sobrinus

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7
Q

T/F: streps evolve quickly

A

True!
it exchanges DNA by transformation

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8
Q

What is glomerulonephritis and what is it caused from?

A

it makes antibodies against filtration system of kidney due to post infection of strep

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9
Q

Which has more diverse infectious diseases: staph aureus or strep pyogenes?

A

strep pyogenes

include: skin infections, throat & respiratory infections, scarlet fever, strep toxic shock, pneumonia

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10
Q

T/F: strep death rates didn’t start going down til antibiotics were developed

A

False!
- unknown why… maybe due to less toxins or better hygiene

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11
Q

Pneumonia is usually caused from _______ and less likely from __________.

A

usually= S. pneumonia
less likely= S. pyogenes Group A

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12
Q

Toxic Shock Syndrome can be caused from:

A

Staph. aureus and strep. pyogenes

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13
Q

What is a key virulence factor that have long fibrillar molecules and is variable in strep pyogenes?

A

M protein

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14
Q

T/F: S. pneumonia have M protein too

A

False!
Only Strep. pyogenes

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15
Q

What does M protein do?

A
  • extend from surface of a cell… protein capsule
  • inhibit phagocytosis
  • bind host peptides with roles in immunity
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16
Q

What is the toxin involved in scarlet fever?

A

Erythrogenic toxins
Pyrogenic exotoxins

17
Q

How do SpeA/C (erythrogenic toxins) stimulate inflammation?

A

travel on macrophages to stimulate cytokine production and give an overall systemic toxic shock

18
Q

Similar to Protein A involved in staph. aureus, what is involved in strep. pyogenes?

A

Protein G non-specifically binds in strep. pyogenes

19
Q

How is strep. pyogenes transmitted?

A

respiratory drops, exchanging secretions, direct skin contact in children

20
Q

How is strep. pyogenes tested?

A

quick antigen detection test

21
Q

What is the tx for strep. pyogenes?

A

topical antibiotics (Neosporin), penicillin, cephalosporins, clindamycin

22
Q

T/F: There are vaccines for S. pyrogenes

A

False!
no vaccines for strep. pyogenes but there are for strep. pneumoniae