Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Module 2 vet med > Non regenerative anaemia > Flashcards

Non regenerative anaemia Flashcards

1
Q

What is non regenerative anaemia

A

A decreased production of red blood bone marrow cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Is this caused by a bone marrow disease?

A

Yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is more common secondary or primary non regenerative anaemia

A

Secondary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is secondary non regenerative anaemia

A

Diseases outside the bone marrow affects the bone marrows ability to produce new red cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What can be causes of secondary non regenerative anaemia

A

Nutritional deficiencies
Inflammation
Chronic renal disease
Others like liver disease etc.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What types of deficiencies can be associated with nutritional deficiency anaemia

A

Protein deficiency
Mineral deficiency
Vitamin deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Why is iron important in the blood

A

Essiential component of haem which carries oxygen in rbcs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What happens in iron deficiency anaemia

A

Interferes with Haemoglobin production which causes decreased production of rbcs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What type of cells are produced in iron deficiency anaemia

A

Hypochromic microcytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What happens to the red cell indices in relation to iron deficiency anaemia

A

Decreased MCV
Decreased MCHC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is a hypochromic microcyte cell

A

Paler in colour and small cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Causes of iron deficiency anaemia

A

Chronic external blood loss- haemorrhage
GI ulceration
Neoplasia
Parasites
Clotting disorder
Inflammatory GI disease
Decreased iron intake

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What type of non regenerative anaemia can appear regenerative in early stages

A

Iron deficiency anaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What type of cells in anaemia of inflammation

A

Normocytic normochromic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What other type of anaemia does an iron deficiency go along with

A

Anaemia of inflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What do cytokines do in anaemia of inflammation

A

Inhibit epo production or BM progenitor cells so reduce rbc production

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Anaemia secondary to chronic renal disease is caused by

A

Functional marrow failure due to reduced erythropoietin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is erythropoietin

A

Hormone that tells BM to make rbcs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What type of cells are involved with anaemia secondary to chronic renal disease

A

Normocytic normochromix

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is azotemia

A

Increase in products in the blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What is isothenuria

A

Change in concentration of the urine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What is primary non regenerative anaemia

A

Disease within the bone marrow that affects ability to produce new rbcs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What is hypoplastic anaemia

A

Producing less

24
Q

What is aplastic anaemia

A

Producing none

25
Q

What is bone marrow neoplasia

A

Cancer

26
Q

What happens in primary hypoplastic/ aplastic anaemia

A

Cellularity of BM is reduced

27
Q

What is pure red cell aplasia

A

Only affects the red blood cell line

28
Q

What are causes of pure red cell aplasia

A

Immune mediated
Infectious
EPO replacement therapy
Preleukamic conditions

29
Q

When the anaemia involves many cell lines what is this referred to as

A

Aplastic anaemia

30
Q

What is classic aplastic anaemia classified by

A

Pancytopenia

31
Q

What are the causes of classic aplastic anaemia

A

Idiopathic
Drugs
Chemicals
Radiation
Infectious agents

32
Q

What is panocytopenia

A

Reduction or absence of all blood cell lines

33
Q

In pancytopenia development is usually

A

Gradual starting with cells with shorter lifespan

34
Q

What is the cell process involving pancytopenia

A

Granulocytes to platelets to erythroytes

35
Q

Examples of causes of pancytopenia

A

Bracken poisoning- cattle
Estrogen, sulphadiazine
Parvovirus
Feline leukaemia virus
Sporadic
Bleeding calf syndrome

36
Q

What is another name for erythrocytosis

A

Polycynthaemia

37
Q

What is erythrocytosis

A

Abnormally increased red cell mass

38
Q

What is increased in erythrocytosis

A

Rbc count
HCT
PCV
Hb levels

39
Q

What are the two types of erythrocytosis

A

Absolute
Relative

40
Q

Absolute erythrocytosis can be

A

Primary or secondary

41
Q

What is primary erythrocytosis

A

Not controlled by EPO

42
Q

What is secondary erythrocytosis

A

Due to increased EPO production

43
Q

What is the most commonly encountered form of erythrocytosis

A

Relative

44
Q

What happens in relative erythrocytosis

A

Increased rbc, PCV and Hb levels due to decreased plasma

45
Q

What is the main cause of erythrocytosis

A

Dehydration

46
Q

What signs to look for in relative erythrocytosis

A

Clinical signs of dehydration
Increased protein levels
Splenic contraction

47
Q

What is the name for increased protein levels

A

Hyperalbuminaemia

48
Q

What is primary absolute erythrocytosis also referred as

A

Polycynthaemia vera

49
Q

What is Polycynthaemia vera

A

When we are making more rbcs that we should be

50
Q

What type of erythrocytosis is an uncontrolled expansion of red cell mass associated with

A

Absolute erythrocytosis

51
Q

What is secondary erythrocytosis

A

Excess erythropoietin production

52
Q

Secondary erythrocytosis can be classified into two categories of

A

Appropriate
Inappropriate

53
Q

Examples of appropriate eryhtrocytosis

A

Hypoxia- fundamental stimulus to eryhtropoeisis

54
Q

Causes of chronic hypoxia

A

Cardiovascular disease
Living at altitude
Chronic respiratory disease

55
Q

Causes of inappropriate erthryocytosis

A

Kidney neoplasms
Non neoplastic disorders

56
Q

Clinical signs of relative erythrocytosis

A

Backy mucous membranes
Sunken eyes
Increased skin tent

57
Q

Clinical signs of absolute erythrocytosis

A

Neurological
Weakness

Module 2 vet med (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions