Nitroglycerine

Question 1

Brand Name for Nitroglycerin

Answer 1

Nitro-Stat
Nitro-Bid
Tridil

Question 2

Drug Class for Nitroglycerin

Answer 2

Vasodilator

Question 3

Indications for Nitroglycerin

Answer 3

Acute angina pectoris
Ischemic chest pain
Hypertension 
CHF
Pulmonary Edema

Question 4

Action of Nitroglycerin

Answer 4

Smooth muscle relaxant acting on vasoculature, bronchial, uterine, intestinal smooth muscle.
Dilation of arterioles and veins in the periphery.
Reduces preload and afterload, decreasing workload of the heart and thereby myocardial oxygen demand

Question 5

Contraindications of Nitroglycerin

Answer 5

Hypotension 
Hypovolemia
Intracranial Hemorrhage 
Pericardial tamponade
Severe bradycardia or tachycardia 
RV infarction
Previous administration in last 24 hours: tadalafil (Cialis) (48 hours), vardenafil (Levitra), sildenafil (Viagra)

Question 6

Adverse Effects of Nitroglycerin

Answer 6

Headache 
Dizziness
Weakness 
Reflex tachycardia 
Syncope
Hypotension 
Nausea Vomiting 
Dry mouth 
Muscle twitching
Diaphoresis

Question 7

Precautions for Nitroglycerin

Answer 7

Not to be given if patient had ED drugs within past 48 hours

Question 8

Dose of Nitroglycerin

Answer 8

Adult: 0.4 mg SL May repeat in 5 minutes to a max of 3 doses.
IV infusion 10 mcg/Mom increase by 10 mcg/min every 3-5 minutes until desired effect with a max dose of 200 mcg/min

Pedi: Not recommended