Hydroxocobalamin Flashcards

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1
Q

Brand Name of Hydroxocobalamin

A

Cyanokit

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2
Q

Drug Class of Hydroxocobalamin

A

Antidote

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3
Q

Indications for Hydroxocobalamin

A

Treatment of known or suspected cyanide poisoning

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4
Q

Action of Hydroxocobalamin

A

Binds with cyanide to form nontoxic cyanocobalamin (Vitamin B12) preventing its toxic effects
Excreted regally

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5
Q

Contraindications for Hydroxocobalamin

A

None in Emergency setting

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6
Q

Adverse Effects of Hydroxocobalamin

A
Hypertension 
Allergic reaction 
GI bleeding
Nausea Vomiting
Dyspepsia (heart burn)
Dyspnea
Dizziness
Headache 
Injection site reaction
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7
Q

Precautions for Hydroxocobalamin

A

Not compatible in same IV line with many other medications

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8
Q

Dose of Hydroxocobalamin

A

Adult: 5 grams IV infusion over 15 minutes at a rate of 15 ml/min. May repeat once at same dose to max of 10 grams.

Pedi: 70 mg/kg IV. May be repeated once at same dose

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