Glucagon

Question 1

Brand Name of Glucagon

Answer 1

Glucagen

Question 2

Drug Class of Glucagon

Answer 2

Hormone

Question 3

Indications for Glucagon

Answer 3

Altered LOC with hypoglycemia

Reversal agent in beta blocker and calcium channel blocker overdoses

Question 4

Mechanism of Action of Glucagon

Answer 4

Increase blood glucose level by stimulating glycogeuolysis
Unknown mechanism of stabilizing cardiac rhythm in beta blocker overdose
Decrease gastric motility and secretions

Question 5

Contraindications for Glucagon

Answer 5

Hypersensitivity

Hyperglycemia

Question 6

Adverse Effects of Glucagon

Answer 6

Dizziness 
Headache 
Hypertension 
Tachycardia 
Nausea 
Vomiting 
Rebound Hypoglycemia

Question 7

Precautions for Glucagon

Answer 7

Not effective if patient does not have any stored glycogen

Question 8

Dose & Administration of Glucagon

Answer 8

Adult:
1.0 mg IM, may be repeated in 10 minutes
Ca & Beta Blocker: OD: 3-10 mg SIVP followed by a 3-10 mg/hour infusion

Pedi:
Hypoglycemia: 0.03-0.1 mg/kg IM/IO/SQ/SIVP repeated in 20 minutes.
Ca & Beta Blocker: 0.05-0.15 mg/kg IV/IO over 3-5 minutes
Followed by 0.05-0.10 mg/kg/h infusion