Morphine

Question 1

Brand Name for Morphine

Answer 1

Roxanol, M.S. Contin

Question 2

Drug Class of Morphine

Answer 2

Opioid Analgesic (Schedule II narcotic)

Question 3

Indications for Morphine

Answer 3

Severe CHF
Acute pulmonary edema
Chest pain secondary to acute MI
Analgesia for moderate to severe acute and chronic pain

Question 4

Action of Morphine

Answer 4

Alleviates pain through CNS action
Suppresses fear and anxiety centers in the brain
Depresses brainstem respiratory centers
Increases peripheral venous capacitance and decreases venous return
Decreased preload and afterload which decrease myocardial oxygen demand

Question 5

Contraindications for Morphine

Answer 5

Head injury
Exacerbated COPD
Depressed respiratory drive
Hypotension 
Undiagnosed abdominal pain
Decreased LOC
Suspected Hypovolemia
Patients who have taken MAOI’s within 14 days

Question 6

Adverse Effects of Morphine

Answer 6

Confusion
Sedation
Headache 
CNS depression
Respiratory depression 
Apnea
Bronchospasm
Dyspnea
Hypotension 
Syncope
Bradycardia 
Tachycardia 
Nausea Vomiting
Dry mouth

Question 7

Precautions for Morphine

Answer 7

Potentiates sedative Effects of phenothiazines (promethazine)
CNS depressants may potentiate Effects
MAOI’s may cause paradoxical excitation

Question 8

Dose of Morphine

Answer 8

Adult: STEMI 2-4 mg SIVP repeat dose 2-8 mg at 15 minute intervals. Pain control ( medical direction)

Pedi: 0.1-0.2 mg/kg IV/IO/IM/SC with max dose of 5mg