Clopidogrel Flashcards
1
Q
Brand Name of Clopidogrel
A
Plavix
2
Q
Drug Class of Clopidogrel
A
Thienopyridine Antiplatelet
3
Q
Indications for Clopidogrel
A
ST elevation MI (STEMI)
Moderate to high risk non-ST elevation MI (NSTEMI)
Acute coronary syndrome
Sub for aspirin
4
Q
Action of Clopidogrel
A
Inhibits platelet aggregation by blocking activation of the glycoprotein llb/llla complex
5
Q
Contraindications of Clopidogrel
A
Active GI bleeding
Intracranial hemorrhage
Hypersensitivity
6
Q
Adverse Effects of Clopidogrel
A
Severe neutropenia TTP GI Hemorrhage Cerebral Hemorrhage Angioedema Stevens-Johnson syndrome
7
Q
Precautions for Clopidogrel
A
Nexium and Prilosec (proton pump inhibitors) may inhibit the effects
8
Q
Dose of Clopidogrel
A
Adult: 300-600 mg PO
Pedi: Not recommended