Clopidogrel Flashcards

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1
Q

Brand Name of Clopidogrel

A

Plavix

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2
Q

Drug Class of Clopidogrel

A

Thienopyridine Antiplatelet

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3
Q

Indications for Clopidogrel

A

ST elevation MI (STEMI)
Moderate to high risk non-ST elevation MI (NSTEMI)
Acute coronary syndrome
Sub for aspirin

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4
Q

Action of Clopidogrel

A

Inhibits platelet aggregation by blocking activation of the glycoprotein llb/llla complex

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5
Q

Contraindications of Clopidogrel

A

Active GI bleeding
Intracranial hemorrhage
Hypersensitivity

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6
Q

Adverse Effects of Clopidogrel

A
Severe neutropenia 
TTP
GI Hemorrhage 
Cerebral Hemorrhage 
Angioedema
Stevens-Johnson syndrome
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7
Q

Precautions for Clopidogrel

A

Nexium and Prilosec (proton pump inhibitors) may inhibit the effects

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8
Q

Dose of Clopidogrel

A

Adult: 300-600 mg PO
Pedi: Not recommended

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