new Flashcards

1
Q

antibiotics that cause c diff?

A

clindamycin
co amoxiclav
cephalexin
ciprofloxacin

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2
Q

how does HUS present

A

abdominal pain
fever
pallor
oliguria

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3
Q

c diff - what kind of bacteria?

A

gram positive bacillus

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4
Q

what is the toxin you look for in c diff?

A

toxin A/B

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5
Q

what antibody test do you use in c diff?

A

ELISA

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6
Q

what is merkels rule of 2?

A

2 inches long
in 2 percent of the population
found 2 foot from the ilioceacal junction

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7
Q

what is merkels diverticulum?

A

diverticulum of terminal ileum

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8
Q

what is the management of merkels divericulm

A

radio nucleotide scan T99

surgical excision

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9
Q

thumb printing on barium swallow?

A

mucosal wall thickening - bowel ischaemia

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10
Q

what might be high in bowel ischaemia?

A

high lactate

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11
Q

most common area for bowel ischamia?

A

splenic flexure

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12
Q

what do you get in bowel ischaemia on sigmoidoscopy and biopsy?

A

withering crypts

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13
Q

what is microscopic colitis?

A

where the rectal mucosa looks normal but the biopsy shows abnormalities

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14
Q

name of surgical procedure in hiatus hernia?

A

nissan fundoplication

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15
Q

two types o microscopic colitis?

A

collagenous and lymphocytic

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16
Q

first investigation for colitis?

A

sigmoidosopy

2nd line is colonoscopy

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17
Q

what is angiiodysplasia?

A

arteriovenous malformations in the colon

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18
Q

where do they usually develop?

A

right side of the colon

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19
Q

diagnosis and management of colonic polyps?

A

colonoscopy and polypectomy

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20
Q

name of the tumour suppressor gene which mutations can lead to colon cancer?

A

APC

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21
Q

the two genetic conditions which pre dispose to colon cancer?

A

FAP

HNPCC

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22
Q

which one of FAP and HNPCC pre disposes to other forms of cancer?

A

HNPCC
colon
ovarian
endometrial

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23
Q

where does colon cancer spread?

A

liver, lung, bone

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24
Q

whats the name of the new test used to detect haemoglobin?

A

FIT instead of FOBT

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25
what age of people are offered screening for bowel cancer?
50-74
26
difference in staging for colon cancer in rectum and colon?
colon is CT, while rectum is MRI
27
what can be used to monitor response to treatment ?
CEA
28
surgical procedure for sigmoid cancer
sigmoid cholectomy
29
low sigmoid/ high rectum ?
anterior resection
30
Rectal
Trans anal endoscopic microsurgery. Abdomino perineal resection
31
who should chemo be offered to following surgery?
all Dukes stage C and above
32
what reduces local recurrence in rectal cancer?
radiotherapy
33
what can be used in stage 4 colonic disease or metastatic disease?
cetuximab
34
what chemo is offered in colon cancer?
5FU and oxaliplatin
35
in woman with IBS symptoms - what should you bear in mind?
ovarian cancer - have a low threshold for suspicion
36
in IBD, inflammation starts in rectum. what is this called?
proctatitis
37
In UC, where does the inflammation not go beyond?
ilio caecal valve
38
what kind of inflammation do you get in UC?
superficial, affecting only the mucosa and submucosa
39
histological changes?
acute crepitis ad crypt abcesses
40
what is pentasa?
5 ASA
41
non caveating granuloma?
crohns
42
what kind of inflammation do you get?
Deep, transmural inflammation that can cause fissures and gives the mucosa a cobblestone appearance
43
what drug can you use in UC but not in crohns?
mesalazine
44
where is vitamin b12 absorbed/
ileum (bileum) | in crohns that affects terminal ileum, can get anaemia and b12 deficiency
45
what is the immunosuppressant that is used in IBD?
infliximab
46
what is th standard investigation of haemorrhoids?
proctoscopy
47
symptoms of haemorrhoids?
itch, pain, bleeding
48
when would someone with symptoms of haemorrhoids get a sigmoidoscopy?
if over 50
49
what bulking agents can you use in haemarrhoids?
fybogel
50
treatment for grades 1-3
injection sclerotherapy | band ligation
51
treatment of grade 4 haemarrhoids?
open or stapled heamorrhoidectomy
52
passing glass on defamation?
fissure
53
management of fissures?
``` stool softeners (laxido) GTN/diltizem ointment botox injections ```
54
opening up of fistula to allow drainage and healing?
fistulotomy
55
if anal sphincter is involved, what do you insert to allow drainage and healing of the access from inside out?
seton drain
56
management of rectal prolapse?
surgery
57
name of procedure for rectal prolapse
rectoplexy
58
what is worms treated with?
mebendazole (whole family)
59
what cancer do you get in the anal canal
SCC
60
anal cancer more common in what kind of patients
HIV and syphillis
61
if anal cancer above pectate line where does it spread? | if below pectate line?
above spreads to pelvic nodes | below spreads to inguinal
62
management of anal cancer?
chemo/radiotherapy