Neurotransmission and Drugs Flashcards

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1
Q

Any molecule to binds to a receptor

A

Ligand

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2
Q

The reabsorption of a neurotransmitter by a neurotransmitter transporter in the presynaptic neuron

A

Reuptake

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3
Q

Determine the effect of a ligand

A

Postsynaptic receptors and channels

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4
Q

Most common neurotransmitter found throughout the brain

A

Glutamate

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5
Q

Is Glutamate inhibitory or excitatory?

A

Exitatory

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6
Q

Ionotropic receptor that allows for flow of multiple ions, causing depolarization

A

AMPA

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7
Q

Ionotropic receptor that contains magnesium. Requires relatively intense depolarization to open channels

A

NMDA

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8
Q

Second most common neurotransmitter in the brain, Most inhibitory neurotransmitter

A

GABA

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9
Q

Excitatory and Inhibitory neurotransmitter that activates muscles. Found in the brain and the PNS

A

Acetylcholine (ACh)

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10
Q

Synapses between motor neurons and muscle fiber

A

Neuromuscular junctions

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11
Q

Toxic chemical weapon that inhibits ACh, lethal

A

Sarin

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12
Q

Family of neurotransmitter that includes Epinephrine, Norepinephrine, and Dopamine

A

Catecholamines

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13
Q

Neurotransmitter that mobilizes brain and body for action

A

Norepinephrine

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14
Q

Autonomic nervous system responsible for activating fight or flight

A

Sympathetic Nervous System

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15
Q

brain stem nuclei that produces norepinephrine

A

Locus Coeruleus

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16
Q

Neurotransmitter responsible for movement, reward-seeking, and motivation

A

Dopamine

17
Q

Neurotransmitter that affects happiness, sleep, and appetite

A

Serotonin (5-HT)

18
Q

Brain stem nuclei that produces Serotonin

A

Raphe Nuclei

19
Q

Family of neurotransmitter that includes Endorphins and Enkephalin

A

Opioids

20
Q

neurotransmitter that can reverse neurotransmission by returning to the presynaptic side

A

Nitric Acid

21
Q

Molecule that enhances function of synapse (enhance either EPSPs or IPSPs, depending on the synapse)

A

Agonist

22
Q

Molecule that reduces function of synapse (reduce either EPSPs or IPSPs, depending on the synapse)

A

Antagonist

23
Q

Agonist that stimulates the release of and/ or prolongs a neurotransmitter

A

Presynaptic Agonist

24
Q

Agonist that activates receptors by mimicking a neurotransmitter

A

Postsynaptic Agonist

25
Q

Antagonist that prevents the release of a neurotransmitter

A

Presynaptic Antagonist

26
Q

Antagonist that blocks receptors

A

Postsynaptic Antagonist

27
Q

Molecule that induces the opposite of a synapse’s function

A

Inverse Agonist