Neurotransmission and Drugs Flashcards
Any molecule to binds to a receptor
Ligand
The reabsorption of a neurotransmitter by a neurotransmitter transporter in the presynaptic neuron
Reuptake
Determine the effect of a ligand
Postsynaptic receptors and channels
Most common neurotransmitter found throughout the brain
Glutamate
Is Glutamate inhibitory or excitatory?
Exitatory
Ionotropic receptor that allows for flow of multiple ions, causing depolarization
AMPA
Ionotropic receptor that contains magnesium. Requires relatively intense depolarization to open channels
NMDA
Second most common neurotransmitter in the brain, Most inhibitory neurotransmitter
GABA
Excitatory and Inhibitory neurotransmitter that activates muscles. Found in the brain and the PNS
Acetylcholine (ACh)
Synapses between motor neurons and muscle fiber
Neuromuscular junctions
Toxic chemical weapon that inhibits ACh, lethal
Sarin
Family of neurotransmitter that includes Epinephrine, Norepinephrine, and Dopamine
Catecholamines
Neurotransmitter that mobilizes brain and body for action
Norepinephrine
Autonomic nervous system responsible for activating fight or flight
Sympathetic Nervous System
brain stem nuclei that produces norepinephrine
Locus Coeruleus