Learning and Memory Part 2 Flashcards
The neural representation of memories
The engram
First researcher of brain mechanisms of learning and memory. Discovered that cortical transections didn’t impact learning but large lesions did
Karl Lashley
Theory that all areas of the cortex are equally involved in memory
Equipotentiality
Theory that the ability to make new memories depends on brain mass
Mass Action
Suffered from epilepsy as a child due to a bike accident. Had his hippocampus removed which stopped seizures but also lost the ability to form new episodic memories (anterograde amnesia)
Patient H.M.
The inability to form new memories
Anterograde amnesia
Has a memory of 30 seconds or less due to anterograde amnesia, caused by lesion of the hippocampus. Loves his wife though <3
Clive Wearing
Theory that experience can leave a memory trace by causing long-lasting connections in synaptic connections
The Synaptic Plasticity Hypothesis
Theory that if one cell repeatedly excited another, the efficacy of the synapse between them will increase
Hebbian plasticity
Repetitive, high frequency stimulation of a presynaptic neuron induces a long-term increase of the synapse with the postsynaptic neuron
Long-term Potentiation (LTP)
Carries information from an experience to the hippocampus
Entorhinal cortex
First information station (cell group) of synaptic flow of the hippocampus
Dentate Gyrus (DG)
Second information station (cell group) of synaptic flow of the hippocampus
CA3 pyramidal cells
Third information station (cell group) of synaptic flow of the hippocampus
CA1 pyramidal cells