Neurology Flashcards
Review
What are the symptoms found in Cortical Dementias
Aphasisa, Apraxia, agnosia, amnesia, visual spatial defects, Palmomental reflext, snout and routing reflexes and gegenhalten resistance
What are the symptoms found in Sub-Cortical Dementias
Mental slowness, bland look, tremor, bradykinesia, executive function (Frontal lobe, test with verbal fluency, perseveration, r/l orientation, calculation, similarities, cognitive estimates, proverbs)
Describe the function of the orbitofrontal sub-system
Maintains socially appropriate behaviors (lesions cause risk taking, impulsivity, anger outbursts, and the frontal disinhibition syndrome) Remember that the orbitofrontal area inhibits the limbic system and a lesion will cause primitive emotions to be unregulated
How do you differentiate orbitofrontal disinhibition from mania?
orbitofrontal disinhibition will have diminished cognitive abilities compared to mania
Describe the function of the mesial frontal sub-system
Maintains drive for socially contact, lesions here will cause an apathy and disinterest in socialization. Not Depression.
Describe the function of the dorsal lateral subsystem
Responsible for organization and planning (executive system proper) Lesions here causes difficulty with the synthesis of linking complicated tasks, such as cooking, balancing a check book…executive syndrome
During the 3rd week of embryonic development the embryo divides into three parts. Name them and what they give rise to.
Epidermal layer- Skin, Nails, Sweat Glands, CNS
Mesodermal Layer- Bones, cartilage, muscle, vascular tissues
Endodermal layer- Gut/Respiratory system.
What week in embryonic development does the Neural Tube form?
Week 4
At week 8 the embryonic CNS system has developed into the Forebrain, Midbrain and hindbrain. What will these sections divide into?
Forebrain (Prosencephalon)- Telencephalon, Diencephalon
Midbrain (Mesencephalon)- Mesencephalon
Hindbrain (Rhombencephalon)- Metenecephalon and Myelencephalon
When does an individual have the most neurons in their life?
4.5 months in development.
When does the brain peak in size?
Around age 6
What are the clinical features/diagnosis of trigeminal neuralgia?
A: Paroxysmal attacks of pain lasting from a fraction of a second to 2 minutes, affecting 1 or more divisions of the trigeminal nerve and fulfilling criteria B and C (below).
B: Pain has at least 1 of the following characteristics: intense, sharp, superficial or stabbing; or precipitated from trigger areas or by trigger factors.
C: Attacks stereotyped in the individual patient.
D: No clinically evident neurologic deficit.
E: Not attributed to another disorder.
Describe Anomic Aphasia
In anomic aphasia, individuals are not able to name objects. Comprehension and naming remain intact. This condition is often the result of small strokes.
Describe Conduction Aphasia
Conduction aphasia involves the inability to repeat, but comprehension remains intact. This is described as a fluent aphasia, and the lesion is an embolic stroke localized to the temporal or parental lobe.
Describe Weirnicke aphasia
Wernicke aphasia is a fluent aphasia with a loss of comprehension, repetition, and naming. Paraphasia is a feature of this disorder that includes incorrect, meaningless, nonsensical words. The lesion is localized to the temporal or parietal lobes.