Neurology Flashcards
AChE in amniotic fluid and AFP in maternal fluid are indicative of
Open neural tube defect (AChE is only CSF)
Hydrocephalus ex vacuo is associated to
Neuronal loss (stroke, trauma, dementia, untreated HIV)
What’s Pseudotumor cerebri ?
High ICP in the absence of ventricular enlargement (idiopathic)
Young obese woman with headache, papilledema and vision problems. No other history. Suspect
Pseudotumor cerebri
Communicating vs non-communicating hydrocephalus
- No ventricle obstruction, drainage problem. Ventricles communicate
- Ventricle Obstruction
Vestibulopathy features
Sudden onset
Tandem walk is ok
Opiates action mec
Bind to Mu receptor/
- on Primary neuron: reduces Ca+2 influx -> less NTs release
-on post synaptic mb: increases K influx -> Hyperpol
Local anesthetics mec
- block Na+ channels -> decreases AP propagation
BZD mec
Increase Cl- influx at GABA-A receptors
Obstruction of cerebral aqueduct affects
3rd and lateral ventricles
Obstruction of foramina of Monro affects
Lateral ventricles only
Lat foramina of Luschka and medial foramen of Magendie affects
4th, 3rd and lat ventricles
Reactivation of HSV occurs via which protein?
Kinesin (anterograde agonal transport)
Dynein is important in which phase of HSV?
Latent
Tuberous sclerosis complex features
-ash leaf macula
-hamartomas
-tuberin - hamartin complex affected
Severe traffic accidents can cause
Diffuse axonal injury - disruption of white matter tracks
Which segments are responsible for the tricipital reflex
C7-C8
Which segments are responsible for bicipital reflex
C5-C6
Lesions before pons affect ____ of face
Ipsilat upper segment (in rel to lesion)
First line treatment for essential tremor
Propranolol
Núcleos del hipopótamo que reg hambre
Ventromedial: saciedad -> daño lleva a hiperfagia
Lateral: hambre -> daño lleva a anorexia
Which nucleus reg sleep
Suprachiasmatic
In general what’s the most common side effect of BZD?
Sedation
*diazepam
Which drugs should be avoided when using BZD?
Barbiturates
Neuroleptics
1st generation anti-histaminecs
Which conditions predispose to Carpal tunnel sd ?
Pregnancy
DM
Hemodialysis
Hypothyroidism
RA
Von Hippel-Lindau features
-Cerebellar (angiomatous lesions) and retinal Hemangioblastomas
-pheochromocytoma
-renal cell carcinoma
Axonal Rx due to trauma produces
Wallerian degeneration: distal to the point of injury.
Rounded cell + nucleus and nissl substance to the periphery
NFT2 features
Bilat vestibular schwannomas (hallmark)
Hearing loss
Tinnitus
Imbalance
NFT1 features
Skin manifestation (café-au-lait macules)
Neurofibromas
Optic nerve fibromas
Pigmented nodules in iris (Lisch nodules)
Rapidly progressive dementia + myoclonus + brain atrophy, think of
Creutzfeldt-Jakob disease (prion disease)
Musculocutaneous nerve fx
Arm addiction
Elbow flexion
Lat forearm sensory inervation
